Physiological causes of infertility in the elderly
With the development of society and the change of people's ideas, more and more women choose to postpone the childbearing age. However, the aging of childbearing has brought a series of physiological obstacles, and the problem of infertility has also increased. This article will elaborate on the physiological causes of infertility in the elderly from four aspects.
Egg quality decline
As women grow older, their ovarian function gradually declines, and the number of eggs available in their ovaries becomes less and less. At the same time, the quality of eggs in the ovary will also decline, including developmental retardation, chromosome aberration and other problems. This has led to the difficulties of the elderly women in childbirth, and the infertility rate has also increased. A study shows that the risk of chromosomal abnormalities in women aged 40 is 10 times higher than that in women aged 30. In this case, the fertilized egg is easy to lose important genetic information, which leads to pregnancy failure.
In addition, the decline in egg quality of elderly women also affects the successful pregnancy rate and the health of fetal development. An increase in the number of abnormal chromosomes in eggs may lead to early embryonic death and an increased risk of birth defects.
Endometrial senescence and thickness decline
The endometrium is the place for embryo implantation, which is very important for pregnancy. The endometrium of elderly women will generally appear aging and thickness decline.
With age, the regenerative capacity of endometrial cells decreases, and blood supply decreases, leading to endometrial thinning. This makes it easy for the embryo to fail to implant in the endometrium, leading to infertility. Research shows that women over 35 years old have more obvious problems of endometrial thinning than young women.
Quality changes of uterine fibroids and mucus
Uterine myoma is a common gynecological tumor, especially in elderly women. The existence of hysteromyoma will lead to abnormal uterine structure, which will affect the implantation of embryos. Research shows that the presence of uterine fibroids will increase the risk of failed pregnancy.
In addition, the physiological environment of elderly women will also affect the quality of uterine mucus. Mucus is an obstacle that an egg must pass through when it passes through the fallopian tube, which is crucial for embryo implantation. However, with the increase of age, the quality and quantity of mucus in women will decline, which will reduce the passing ability of embryos. This is also an important reason for the infertility of elderly women.
Abnormal hormone level
Ovarian hormone is an important substance to maintain the normal function of female reproductive system. However, with the growth of age, female hormone levels gradually decline. Abnormal hormone levels can lead to ovulation dysfunction, ovarian dysfunction and other problems.
For example, luteal phase deficiency is one of the common problems of elderly women. Insufficient luteal phase means that the progesterone secreted by the ovary is insufficient, which will lead to the instability of the endometrium and cannot provide good implantation conditions for the embryo. In addition, abnormal hormone levels may also lead to menstrual cycle disorder, resulting in irregular ovulation, further increasing the risk of infertility.
Summary
The physiological causes of infertility in the elderly mainly include the decline of egg quality, endometrial aging and thickness decline, changes in the quality of uterine fibroids and mucus, and abnormal hormone levels. With the growth of age, these factors will interact, leading to a decline in women's ability to conceive, making older women face the risk of infertility. Therefore, in the late birth planning, women should pay attention to their physiological conditions in advance and actively seek the help and guidance of doctors.
