Male elder childbearing may affect children's development
Male elder childbearing refers to the childbearing of men over 35 years old. With social progress and changes in family values, more and more men choose to postpone childbearing. However, some studies have shown that older men may have an impact on children's development and health. 1. Increased risk of genetic mutation
The quality of male germ cells will decline with age, which may increase the risk of genetic mutation. Long term studies have found that compared with young fathers, children of older fathers have a higher risk of certain genetic diseases. For example, the older the father, the higher the chances of his children suffering from autism, psychosis, cerebral palsy, congenital heart disease and other neurological and cardiovascular diseases. Research shows that compared with young fathers, fathers and children over 40 years old may have a 20-50 fold increased risk of autism. A study by the McKittrick Cancer Center of the University of Pittsburgh found that compared with young fathers, the risk of leukemia and brain tumor in children of fathers over 50 was twice and three times higher, respectively. These findings suggest that the elderly male fertility may increase the risk of some genetic diseases.
2. Sperm DNA damage and quality decline
Older men may also lead to sperm DNA damage and quality decline. A study found that men over 35 years old have poor DNA integrity and lower sperm quality. The damage and quality decline of sperm DNA will directly affect the quality of fertilized eggs and embryonic development, which is likely to lead to the termination of embryonic development or abnormal development. In addition, male aging is also associated with an increased risk of sperm chromosomal abnormalities. The study found that fathers over 50 years old may make their children suffer from diseases related to chromosome abnormalities, such as Down syndrome, which may increase the risk 4-5 times.
3. Influence of father's health
The relationship between male elderly childbearing and father's health can not be ignored. With the growth of age, men's physiological functions gradually decline, which may lead to chronic diseases, cardiovascular diseases and other health problems. These health problems may affect men's fertility and children's health. The study found that older fathers had a higher risk of chronic diseases such as hypertension, diabetes and cardiovascular disease than younger fathers. These chronic diseases may not only have a negative impact on sperm quality, but also increase the risk of children suffering from related diseases.
4. Parents' lifestyle and environmental factors
Male elder childbearing may be related to parents' lifestyle and environmental factors. Older fathers usually work under pressure, and their living habits may be unhealthy, such as irregular diet and insufficient exercise. These lifestyles will have an impact on the quality of male fertility. In addition, some environmental factors may also have a negative impact on male fertility. For example, men's long-term exposure to harmful substances, exposure to high radiation environment or the use of certain drugs may have an impact on sperm quality and DNA, and thus affect the development and health of children.
summary
Older male childbearing may lead to children's development problems and health risks. The increased risk of genetic mutation, sperm DNA damage and quality decline, the influence of father's health status, as well as parents' lifestyle and environmental factors, are all important factors that may affect the development of children when men give birth at an advanced age. Therefore, for older men, it is necessary to fully understand and understand these potential risks, and make reasonable trade-offs and choices when deciding on childbearing. At the same time, the family and society should provide more support and education to guide men to establish correct fertility concepts and maintain a healthy fertility environment.
