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How to judge the quality of IVF eggs?

How to judge the quality of IVF eggs?



How to judge the quality of IVF eggs?

In the development of IVF technology, the quality of eggs is a crucial factor. The quality of eggs is directly related to the success rate of fertilization and embryo development. So, how to judge the quality of IVF eggs? The following four aspects of egg morphology, vitality, chromosome number and endoplasmic reticulum quality are described in detail.

1、 Morphology of egg

The shape of the egg has a great influence on its quality. Normal eggs usually present complete and uniform morphology, while abnormal eggs may have abnormal morphological changes. Hospitals often use microscopes to observe the shape of eggs to assess whether they meet normal standards. Abnormal egg morphology may lead to difficulty in fertilization or abnormal embryonic development, thus affecting the success rate of IVF. In addition, the texture of the egg is also an important index to evaluate its shape. Normal egg texture is usually transparent and flexible, while abnormal egg texture may be granular and irregular. These abnormal textures may affect the binding ability of eggs and sperm, thus reducing the success rate of in vitro fertilization.

2、 Egg vitality

The vitality of eggs refers to the biological activity of eggs, and is also one of the important indicators for evaluating the quality of eggs. Vigorous eggs usually have high survival rate and fertilization ability. Hospitals usually judge the vitality of eggs by evaluating their membrane integrity, cytoplasmic activity and cytoplasmic flow. Membrane integrity refers to whether the outer membrane of the egg is intact, which is directly related to the survival rate of the egg. Cytoplasmic activity refers to the activity of the internal quality of the egg cell, such as vacuole content, particle movement, etc. Cytoplasmic flow refers to the flow of various substances in the cytoplasm, which is necessary for the normal metabolism of eggs. By observing and evaluating these indicators, the hospital can judge the vitality level of eggs, thus providing a reference for the success rate of IVF.

3、 Chromosome number of egg

The chromosome number of eggs is one of the important indexes to evaluate their quality. Normal eggs should have the correct number of chromosomes (23 pairs of chromosomes), while abnormal eggs may have chromosome loss, redundancy or structural abnormalities, which are called chromosome abnormalities or chromosome aneuploidy. The eggs with abnormal chromosomes are easy to lead to abnormal embryonic development, increasing the risk of pregnancy failure and fetal malformation. The hospital usually uses PGS (embryonic chromosome screening) technology to evaluate the number of chromosomes in eggs and improve the success rate of IVF. PGS technology can screen out eggs with abnormal chromosomes, reduce the implantation of abnormal embryos, and improve the implantation rate and pregnancy rate of embryos.

4、 Endoplasmic reticulum mass of eggs

The endoplasmic reticulum of an egg is a kind of organelle located in the cytoplasm, which directly participates in the process of egg maturation and embryonic development. The quality of endoplasmic reticulum has an important impact on the quality of eggs. The normal endoplasmic reticulum should have a tight spatial structure and normal functional activity to ensure the normal development of the embryo. Hospitals usually evaluate the quality of the endoplasmic reticulum of eggs by studying the morphology and function of the endoplasmic reticulum in oocytes. The normal endoplasmic reticulum should present a uniform and compact structure, while the abnormal endoplasmic reticulum may present abnormal forms such as expansion and rupture, which may lead to the decline of egg quality and abnormal embryonic development.

summary

Through the evaluation of the above four aspects, we can preliminarily judge the quality of IVF eggs. The shape, vitality, chromosome number and endoplasmic reticulum quality of eggs are all important indicators to evaluate the quality of eggs, which play a key role in improving the success rate of IVF. Therefore, in the implementation of IVF, hospitals need to fully consider the evaluation of these aspects and provide corresponding treatment and auxiliary technology to improve the egg quality and the success rate of IVF.
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