Requirements of IVF on embryo quality
IVF refers to the babies conceived with the assistance of in vitro fertilization and embryo culture technology. The success rate of IVF is closely related to the embryo quality, so the embryo quality is of great significance for IVF. This article will elaborate on the requirements of IVF for embryo quality from four aspects: embryo appearance, embryo development, embryo chromosome abnormalities and implantation timing.
Embryonic appearance
Embryo appearance is one of the important indicators for evaluating embryo quality. A normal embryo should have a relatively regular shape, and embryonic cells should be closely connected with smooth surface. Abnormalities in the appearance of the embryo may indicate problems in the development of the embryo, such as uneven division of the embryo, insufficient number of cells, or cell abnormalities. Therefore, high-quality embryos should have a good appearance, which is conducive to better development and survival rate of embryos in the subsequent culture and implantation process.
In addition, the appearance of the embryo can also reflect the degree of development of the embryo. Mature embryos are healthier and more complete in appearance than immature embryos, and usually have higher implantation and survival rates.
Embryonic development
The degree of embryo development is another important factor in evaluating embryo quality. The degree of embryonic development mainly includes cell division, embryonic stage and cytoplasm quality. During normal development, the embryo will undergo a series of cell division, and eventually form a blastocyst. The better embryonic development is usually characterized by average cell division and smooth embryonic progress. Poor embryonic development is often accompanied by abnormal cell division, development delay and other problems.
In addition, the embryonic stage can also reflect the degree of embryonic development. In the process of culture, the embryo will gradually enter the stage of blastocyst, which is a key turning point of embryo development. Embryos at the blastocyst stage are more mature and stable, and easy to achieve successful implantation.
Embryonic chromosomal abnormalities
Embryonic chromosomal abnormalities are one of the main causes of embryonic development failure. Chromosome abnormalities may lead to delayed, stagnant or incomplete embryonic development. Therefore, it is very important for IVF to have normal chromosome structure and quantity.
Modern medicine has developed a series of chromosome genetic detection technologies, such as PGD (embryonic chromosome genetic diagnosis) and PGS (embryonic chromosome screening). Through these technologies, doctors can conduct genome screening and evaluation on embryos, screen out embryos with chromosome abnormalities, and improve the success rate of IVF.
Implantation timing
Choosing the right implantation time also has an important impact on the success rate of IVF. Generally, the embryo is implanted after a certain period of culture to ensure that the embryo has proper development and maturity. Different hospitals and doctors may have different implantation timing choices, usually after the embryo develops to the blastocyst stage. Choosing the right implantation time can improve the success rate of embryo implantation, thus increasing the success rate of IVF.
Summary
IVF has strict requirements on embryo quality. Good embryo appearance and development degree are important basis for evaluating embryo quality. Embryonic chromosome abnormalities will affect the development and survival of embryos, and selecting appropriate implantation time is also a key factor to improve the success rate of IVF. In the process of IVF, doctors and patients should pay close attention to and evaluate the quality of embryos to select the best embryos for implantation and improve the success rate of IVF.
