New breakthrough points of the third generation of IVF
With the continuous development and innovation of IVF technology, more and more couples are able to realize their reproductive dreams. In the third generation of IVF technology, there have been some new breakthroughs. Let's take a look.
1. Application of PGD technology
One of the new breakthroughs in the third generation IVF technology is the application of PGD (Preimplantation Genetic Diagnosis) technology. PGD technology can screen out embryos carrying genetic disease genes through gene analysis of embryos, so as to select healthy embryos for implantation and reduce the risk of genetic diseases for babies. The application of this technology has greatly improved the success rate of IVF and the birth rate of healthy babies.
At present, many medical institutions around the world have begun to use PGD technology, including the Massachusetts General Hospital affiliated to Harvard University in the United States, Peking Union Medical College Hospital in China and other well-known medical institutions. The application of PGD technology provides couples with more choices of high-quality embryos and helps them better conduct IVF treatment.
2. Further development of in vitro maturation technology
Another new breakthrough of the third generation IVF technology is the further development of In Vitro Maturation (IVM) technology. IVM technology refers to the culture of eggs in vitro to the mature state, and then fertilize with sperm, and finally carry out embryo implantation.
Compared with the traditional IVM technology, IVM technology is more simple and does not require the use of a large number of hormone drugs to promote follicular development. In addition, IVM technology gives more opportunities to women with hormone resistance, polycystic ovary syndrome and other problems, so that they can also realize their reproductive dreams through IVM technology.
Globally, many famous clinics and research institutions are conducting research and application of IVM technology, such as Leiden University Medical Center in the Netherlands, Institute of Reproductive Medicine of the University of New South Wales in Australia, etc. In vitro maturation technology further broadens the scope of application of IVF technology.
3. Attempt of gene editing technology
One of the new breakthroughs of the third generation of IVF is the attempt of gene editing technology. Gene editing technology is to avoid genetic diseases by modifying the gene sequence of embryos. At present, the most widely known gene editing technology is CRISPR-Cas9. Scientists can use CRISPR-Cas9 to repair abnormal genes in the early stage of the embryo, so as to achieve selective implantation of healthy embryos.
Although the application of gene editing technology in IVF is still in its early stage, and there are many ethical and legal problems, it has great potential. Some famous medical and scientific institutions, such as Massachusetts Institute of Technology in the United States and the Obstetrics and Gynecology Hospital affiliated to Fudan University in China, are conducting research and experiments on gene editing technology. In the future, gene editing technology may become an important breakthrough in the field of IVF.
4. Improvement of implantation assistance technology
Another new breakthrough of the third generation of IVF is the improvement of implantation assistance technology. Implantation assist technology refers to providing better implantation environment for IVF embryos after implantation and improving the success rate of implantation.
At present, many improved implantation assistance technologies are developing, such as endometrial preparation technology, implantation process monitoring technology, etc. These techniques can help diagnose problems in the uterine environment, improve the endometrial capacity for embryos, and monitor the implantation of embryos in the uterus, thus increasing the success rate of IVF.
In a word, the third generation of IVF technology has brought many new breakthroughs. It includes the application of PGD technology, the further development of in vitro maturation technology, the attempt of gene editing technology and the improvement of implantation assistance technology. These breakthroughs make IVF technology more safe and reliable, and provide more choices and hope for couples to realize their reproductive dreams.
