Transplantation of ascites in test tube infants
IVF is fertilized and embryo cultured in the laboratory through artificial assisted reproduction technology, and sometimes ascites may occur during embryonic development. Ascites is caused by the accumulation of fluid in the embryo sac, which may adversely affect the development of the embryo. To solve this problem, doctors have developed different forms of transplantation. The following will elaborate on embryo grading, embryo selection, embryo transfer, and post transfer assistance.
Embryo grading
Embryo grading is one of the important steps in the process of IVF. According to the shape, number and quality of cells and other factors of the embryo, evaluation and grading are carried out to select the most potential embryo for transplantation. There are many common embryo grading systems, including Oxford grading method in England, Gardner grading method in America, etc. These grading standards are based on the number and morphological characteristics of embryonic inner and outer cells.
First, according to the development of the embryo, it is divided into different stages, such as 5-6 stages in the early stage, 8-10 stages in the middle stage, 14-16 stages in the late stage, etc. Secondly, according to the quality of embryonic cells, such as cell symmetry, particle distribution, etc., we can judge the development potential of the embryo. Finally, according to the appearance of the embryo, such as the size of the blastocyst cavity, the tightness of the cells, and the internal and external homology of the cells, the embryo was evaluated. Through embryo grading, the most potential embryos can be screened for transplantation, and the success rate of IVF can be improved.
Embryo selection
In the treatment of test tube infant ascites, embryo selection is a very important link. According to the grading results and development of embryos, doctors will select the most promising embryos for transplantation. The commonly used embryo selection methods include suggestions on embryo shelling, embryo sac splitting and embryo early implantation.
The proposal of embryo shelling refers to the selection of embryos that have broken the main outer transparent membrane for transplantation. This kind of embryo is easier to be implanted in the natural physiological state, and usually has a higher success rate of transplantation. Embryo blastocyst splitting proposal refers to the selection of embryos with expanded blastocyst cavity or with small or no complete outer transparent membrane for transfer. The suggestion of early implantation of embryos refers to the selection of embryos on the 5th to 6th day for transfer, because these embryos have better development potential.
Through embryo selection, doctors can select the most suitable embryos for ascites treatment to improve the success rate of transplantation.
embryo transfer
Embryo transfer is one of the key steps in the treatment of ascites in test tube infants. According to the results of embryo selection, doctors will put the rescued embryos into the mother's uterus to help the embryo development and implantation, so as to achieve the transfer of test tube babies.
Embryo transfer is usually performed by vaginal implantation or intraperitoneal implantation. Transvaginal implantation is the most commonly used method of embryo transfer, which is simple and minimally invasive, and is suitable for most IVF patients. Transabdominal implantation is an embryo transfer under laparoscopy. The doctor transfers the embryo into the uterus through a small incision. This method is applicable to some special cases, such as uterine abnormalities, intrauterine adhesions, etc.
Post transplant assistance
After the test tube baby ascites treatment, some auxiliary measures should be taken to promote the development and implantation of embryos. The common auxiliary measures after transplantation include the use of progesterone, addition of culture medium, and auxiliary adhesion treatment.
Progesterone is a synthetic progesterone, which can promote the growth and development of endometrium and improve the implantation rate of embryos. In the process of IVF transplantation, doctors will supplement progesterone according to the specific conditions of patients.
The purpose of adding culture medium is to provide nutrients for embryonic development and promote its development and implantation. The survival rate and implantation rate of embryos can be improved by reasonable selection and addition of culture medium.
Adjuvant adhesion therapy refers to the use of drugs and surgery to improve the adhesion of endometrium and improve the implantation conditions of embryos. Adjuvant adhesion therapy can reduce the occurrence of fetal ascites and improve the success rate of IVF.
summary
The treatment of test tube infant ascites needs comprehensive consideration from embryo grading, embryo selection, embryo transfer and post transfer assistance. Through the grading and selection of embryos, potential embryos can be selected for transplantation to improve the success rate of transplantation. Embryo transfer and auxiliary measures after transfer can promote the development and implantation of embryos, so as to achieve the ascites treatment of test tube infants. Different treatment methods are applicable to different patients and need to be selected according to the specific conditions of patients.
In general, the forms of IVF ascites transplantation are diverse, and with the continuous progress of technology and the accumulation of doctors' experience, these forms are also evolving and improving, providing more possibilities for IVF ascites treatment.
