Effect of progesterone in test tube infants
Progesterone is an important hormone used in artificial insemination, test tube baby and embryo transfer in assisted reproductive technology. Progesterone plays a vital role in the reproductive process. The following will elaborate on the role of progesterone in IVF from several aspects.
1. Promote the growth of endometrium
The growth of endometrium is critical to the success of IVF. Progesterone can increase the blood supply of endometrium, promote the thickening of endometrium, and provide a favorable environment for the implantation of fertilized eggs. The first stage of progesterone treatment is helpful to maintain the growth of endometrium, while continuing progesterone treatment after embryo transfer can further enhance the carrying capacity of endometrium and improve the success rate of embryo implantation.
In addition, progesterone can also regulate the local immune response of endometrium and enhance the capacity of endometrium to hold embryos. It can reduce the immune response of endometrium itself, avoid the adverse effects of antibodies and other substances on embryos, and provide a good environment for the development of embryos.
2. Maintain pregnancy
In IVF, progesterone also plays a key role in maintaining pregnancy. Generally, the ovary will produce corpus luteum after ovulation and secrete a large amount of progesterone to maintain early pregnancy. However, in the process of IVF, the ovarian function may be affected by some factors and cannot produce enough progesterone.
At this time, progesterone replacement therapy can effectively supplement the progesterone that is lacking in IVF or IVF. The supplement of progesterone can effectively regulate the hormone level, promote the further growth of endometrium, and maintain sufficient progesterone secretion of the fetus from pregnancy to the time of pregnancy. This can effectively reduce the risk of abortion and improve the success rate of IVF.
3. Prevention of luteal insufficiency
Luteal insufficiency is a common reproductive system disease. It refers to the deficiency of progesterone secreted by the corpus luteum, which leads to the abnormal growth and maintenance of the endometrium and is prone to early abortion. Progesterone in IVF treatment can prevent the occurrence of luteal insufficiency.
By starting progesterone treatment early after ovulation, progesterone can be supplemented in advance to promote the growth and maintenance of endometrium and prevent the occurrence of luteal insufficiency. A period of progesterone treatment can increase the number of luteal cells and improve the secretion of progesterone, thus improving the pregnancy rate of test tube babies.
4. Reduce the risk of miscarriage
In the process of IVF, the risk of abortion is relatively high due to various reasons. Progesterone supplementation can effectively reduce the risk of abortion and improve the success rate of IVF.
As an important hormone, progesterone can not only promote the growth of endometrium, maintain early pregnancy, prevent luteal insufficiency, but also reduce the risk of abortion by regulating the secretion of luteal cells. The application of progesterone needs to be carried out under the guidance of doctors, and the selection of dose and course of treatment needs to be individually adjusted according to the specific situation of each patient to improve the pregnancy success rate of test tube babies.
Summary
In vitro progesterone (IVP) plays an important role in artificial insemination, IVF and embryo transfer. By promoting the growth of endometrium, maintaining early pregnancy, preventing luteal insufficiency and reducing the risk of abortion, it provides a good pregnant environment for IVF and effectively improves the probability of successful pregnancy. However, the application of progesterone also needs to be carried out under the guidance of doctors to ensure that the dosage and course of treatment are appropriate.
