Is the egg quality of IVF related to age?
The wide application of IVF technology has brought hope to many infertile people, and egg quality is one of the important factors affecting the success rate of IVF. Many people wonder whether the quality of IVF eggs is related to age? The following four aspects will be described in detail: the impact of age on egg quality, physiological changes, chromosome abnormalities and assisted reproductive technology.
Effect of age on egg quality
Age is one of the important factors affecting the quality of female eggs. With the growth of age, the female reproductive system began to show physiological aging changes. Women carry all eggs from birth. With the increase of age, the number and quality of eggs gradually decrease. Research shows that after the age of 35, the quality of female eggs will decline significantly, increasing the risk of chromosomal abnormalities.
In addition, age also affects the maturity and energy of eggs. With the increase of age, the maturity of eggs decreases, and the fertilization rate decreases accordingly. This means that under the same embryo culture conditions, the success rate of older female IVF will be reduced.
Physiological changes
With the growth of age, a series of physiological changes occur in the female body, which affect the quality of eggs. On the one hand, egg quality is closely related to follicular development. With the increase of age, the number of follicles decreases, and the development speed of follicles slows down, thus affecting the maturation of eggs. On the other hand, with the increase of age, the estrogen level in women's body decreases, which has a certain impact on the development and quality of eggs. These physiological changes will lead to the decline of egg quality.
In addition, factors related to living habits and living environment also affect egg quality. For example, smoking, drinking, bad eating habits, stress, etc. may lead to damage to egg quality. Therefore, women should try to avoid these bad habits before IVF treatment to improve the quality of eggs.
Chromosomal abnormality
Age increases the risk of chromosomal abnormalities in eggs, especially in women over 35 years old. Studies have found that specific chromosomal abnormalities, such as Down syndrome, are closely related to the decline of egg quality. This is because with the growth of age, eggs are prone to the errors of non separation and aneuploidy during meiosis, leading to chromosomal abnormalities. Chromosome abnormalities will increase the risk of early embryo abortion and congenital malformations.
Assisted reproductive technology
Because of the adverse effect of age on egg quality, many older women will choose assisted reproductive technology, such as IVF. IVF technology can improve the success rate of fertilization and embryo transfer through a variety of means, thus improving the reproductive opportunities of older women.
For example, through in vitro fertilization (IVF) technology, we can select high-quality eggs for fertilization, and cultivate embryos in the laboratory to select better embryos for transplantation. In addition, egg donation can also be used to solve the problem of poor egg quality.
In conclusion, the quality of IVF eggs is related to age. The increase of age will lead to the decrease of the number and quality of eggs and the increase of the risk of chromosomal abnormalities. However, assisted reproductive technology can compensate for the adverse effect of age on egg quality to some extent. Therefore, older women can improve their fertility opportunities through appropriate assisted reproductive technologies.
