Relationship between follicular reduction and age in test tube infants
IVF is an assisted reproductive technology through in vitro fertilization and embryo transfer, which is often used to treat infertility. However, with the growth of women's age, their ovarian function gradually declined, leading to the reduction of the number of follicles. This article will discuss the relationship between the reduction of follicles in IVF and age, and elaborate it from the physiological, biological, medical and social perspectives.
Physiological perspective: the relationship between the number of follicles and age
Women have a fixed number of follicles at birth, but the number and quality of these follicles gradually decrease with age. This is because the ovarian function of women gradually declines, and the production and release of eggs become unstable. Research shows that women will lose about 90% of their eggs before the age of 30, while at the age of 40, only about 5% of their egg reserves remain.
In addition, the decrease in the number of follicles will also lead to abnormal or dysfunctional ovulation, further increasing the difficulty of pregnancy. Therefore, there is a clear link between female age and IVF success rate.
Biological perspective: fixed fertility
Female fertility is fixed to a certain extent, and age will only bring about a gradual decline in fertility. With the growth of age, the quality of female eggs declines, and chromosomal abnormalities and gene mutations are prone to occur. These problems will affect the development of fertilized eggs and the success rate of embryo implantation, thus reducing the success rate of IVF. Therefore, age is one of the important factors for the success of IVF.
In addition, aging is also related to other physiological problems, such as thin endometrium, ovarian insufficiency, etc. These problems will further affect the success rate of IVF and increase the risk of infertility.
Medical perspective: the influence of age on success rate
Medical research shows that women's age has a direct impact on the success rate of IVF. One study pointed out that the success rate of IVF was about 40% to 50% among women under 35 years old, while the success rate dropped to 10% to 20% among women over 40 years old. This shows that the age of women has an important impact on the quality and quantity of eggs, and affects the success rate of IVF.
In order to improve the success rate of IVF, some hospitals also provide assisted reproductive technologies, such as egg freezing. This can help women collect and retain eggs when they are young for future use. However, even with these assistive techniques, age is still an important limiting factor.
Social perspective: late childbearing trend and IVF
In recent years, with the development of social economy and the rise of women's career pursuit, more and more women choose to have late childbearing. However, late childbearing also brings challenges to IVF. Because of the decrease of follicles due to aging, women with late childbearing need to rely on assisted reproductive technology to achieve their reproductive aspirations. This has led to the increasing demand for IVF technology and the development of related hospitals and institutions.
In conclusion, IVF follicular reduction is closely related to age. From the perspective of physiology, biology, medicine and society, female age plays an important role in the success rate of IVF. With more women choosing late childbearing, the development and application of IVF technology will be more and more extensive.
