How big can test tube baby follicles be?
IVF technology is an assisted reproductive technology, which combines eggs and sperm during in vitro fertilization and embryo culture, and then transfers the fertilized eggs back to the female uterus to help infertile couples realize their reproductive dreams. In IVF technology, the selection of appropriate eggs is crucial to the success rate. Follicle size is an important indicator to determine the degree of oocyte maturation. The following discussion is about the size of test tube baby follicles and the selection of oocytes from the development process of follicles, the selection of follicle size, the quality of eggs and the actual operation of hospitals.
Development process of follicle
In the normal menstrual cycle of women, the follicles will undergo the process of development before the ovaries ovulate every month. On the first day of menstruation, about 5-20 follicles begin to develop, and only one follicle will develop into the dominant mature follicle, while other follicles will stop developing. The diameter of mature follicles is generally about 16-22 mm.
The process of follicular development is generally observed and recorded by ultrasonic examination. The doctor will use transvaginal ultrasound to check and evaluate the follicular development according to the size and number of follicles. When the follicle diameter reaches a certain size, the appropriate time is generally selected for egg collection.
Selection of follicle size
The selection of follicle size is very important in IVF technology, because only mature eggs can be successfully fertilized and developed into embryos. Generally, when the follicle diameter is about 18-20 mm, it is the best choice. At this time, eggs are usually mature and of good quality, with high fertilization and implantation capacity.
The size of follicles should also be considered in combination with other factors, such as female age, ovarian reserve and hormone level. Sometimes, under some special circumstances, it may be necessary to select smaller or larger follicles for egg collection, which requires doctors to make judgments and trade-offs according to the specific situation.
Egg quality
In addition to the size of the follicle, the quality of the egg is also an important factor in selection. The evaluation of egg quality mainly includes the following aspects:
1. The function of the egg endoplasmic reticulum: The endoplasmic reticulum is an important structure in the cell and plays a key role in the maturation and development of the egg. The abnormal function of the egg endoplasmic reticulum may lead to the decline of the developmental ability of the fertilized egg.
2. Chromosome structure of the egg: Chromosome abnormalities may lead to embryo abnormalities and spontaneous abortion. Therefore, the selection of eggs with normal chromosome structure is crucial for the success rate of IVF.
3. Egg shape: Normal eggs usually have better fertilization ability and embryonic development ability. Therefore, when selecting eggs, doctors will observe the morphological characteristics of eggs in detail to evaluate their quality.
Practical operation in hospital
In the actual operation of IVF, the hospital will determine the specific criteria for selecting the size of the follicle for oocyte retrieval according to its own practical experience and technical level. Each hospital has its own personalized operation and standard in IVF technology. Therefore, the specific requirements for selecting the size of test tube baby follicles for oocyte retrieval may also be slightly different.
Generally speaking, the hospital will formulate appropriate plans and standards based on clinical experience and relevant research, combined with the specific conditions and needs of patients. The doctor will combine the ultrasonic examination and other relevant examination results to comprehensively judge the follicle size and egg quality, so as to select the best egg for IVF treatment.
Summary
How large the follicles of IVF can be selected is an issue of great concern in the medical field. By elaborating on the follicular development process, selection of follicle size, egg quality and actual operation of the hospital, we can draw the following conclusions:
1. When the follicle diameter is about 18-20 mm, it is the best choice.
2. The evaluation of egg quality mainly includes the function of endoplasmic reticulum, chromosome structure and morphology.
3. Different hospitals may have slightly different operating standards, and the specific selection should be based on the actual situation of patients.
Therefore, before IVF technology, patients should fully communicate with doctors to understand the specific operating standards and selection requirements, so as to improve the success rate and safety of IVF.
