Why does IVF abortion often happen?
IVF is a method of assisting pregnancy through in vitro fertilization. However, sometimes IVF will miscarry. So, why does IVF abortion often happen? The following will elaborate on physiology, environment, gene and diet.
Physiological cause
A common physiological cause of IVF abortion is endometrial abnormalities. The endometrium is an important environment for implantation. If the endometrium is too thin, too thick, or has polyps, it will lead to embryo implantation failure and abortion. In addition, gynecological diseases such as hysteromyoma and endometriosis will also affect the development and implantation of IVF, increasing the risk of abortion.
In addition to uterine factors, hormone level regulation may also affect the embryonic development of IVF. For example, corpus luteum dysfunction can lead to lutein deficiency, making the embryo unable to implant in the uterus. The imbalance between estrogen and progesterone may also lead to abnormal embryonic development, which may lead to IVF abortion.
In addition, age is also an important factor affecting the abortion rate of IVF. As women grow older, their egg quality gradually declines, and the probability of chromosomal abnormalities and genetic mutations increases, leading to an increased risk of chromosomal abnormalities and abortion in IVF.
environmental factor
Environmental factors are also one of the reasons for IVF abortion. Radiation, chemicals, drugs, etc. exposed in daily life will have adverse effects on embryonic development. For example, long-term exposure to radiation in the working environment, or taking certain drugs that are not recommended during pregnancy, will increase the risk of miscarriage.
In addition, pressure is also an important environmental factor affecting the abortion rate of IVF. Long term physical and mental pressure will affect women's endocrine balance and immune regulation, and increase the possibility of IVF abortion.
Genetic factor
Genetic factors are another important reason for IVF abortion. Chromosome abnormality is one of the main factors leading to natural selection of embryos. Embryos with chromosomal abnormalities have a high probability of automatically terminating pregnancy after implantation, which is one of the reasons why abortion often occurs in the early stage.
In addition, some family genetic diseases will also affect the development and implantation of IVF, increasing the risk of abortion. These genetic diseases may cause chromosome instability of embryos, resulting in abnormal embryonic development and abortion.
Dietary factors
Dietary factors may also affect the abortion rate of IVF. Malnutrition and excessive caffeine intake increase the risk of miscarriage. Malnutrition will lead to malnutrition in the mother's body and affect the nutrition supply and development of the embryo. Excessive caffeine intake will lead to increased uterine contractions and increase the risk of miscarriage.
In addition, the lack of certain vitamins and trace elements in the diet, such as folic acid, vitamin B12, will also increase the possibility of IVF abortion.
summary
The frequent occurrence of IVF abortion can be attributed to physiology, environment, genes and diet. Endometrial abnormalities, hormone level imbalance, aging, radiation and chemicals in the environment, drug use, long-term stress, chromosome abnormalities, family genetic diseases, malnutrition, and excessive caffeine intake may all lead to IVF abortion. For couples preparing for IVF, it is very important to understand these possible reasons and take corresponding preventive measures.
