Common factors of IVF abortion
IVF technology is a kind of assisted reproductive technology, which can help those couples who cannot conceive naturally realize their reproductive aspirations. However, IVF also has certain risks, one of which is abortion. The occurrence of IVF abortion may be related to multiple factors. The common factors of IVF abortion will be described in detail from four aspects: anti embryonic antibody, uterine factor, embryo genetic abnormality and maternal age.
Antiembryonic antibody
Anti embryonic antibodies refer to a class of autoantibodies produced in the body against embryonic antigens. When these antibodies exist in the mother's blood, they will attack the embryonic tissue, leading to IVF abortion. The production of anti embryonic antibody may be caused by abnormal immune system or allergic reaction. If anti embryonic antibodies are detected in the mother's body, doctors can take corresponding treatment measures, such as hormone therapy or immunomodulation therapy, to reduce the risk of abortion.
However, at present, the research on anti embryonic antibody is still relatively limited, and its specific production mechanism and treatment methods still need further exploration and research.
Uterine factor
The health of the uterus is critical to the success of IVF. The thickness, hyperemia and immune status of endometrium will affect the implantation and development of embryos. For example, thin endometrium or insufficient congestion will cause the embryo to be unable to implant firmly, increasing the risk of miscarriage. Uterine diseases such as hysteromyoma and endometriosis may also affect embryo implantation and development.
Therefore, before IVF, women need to receive detailed uterine examinations, such as hysteroscopy, ultrasound, etc., to ensure that the health of the uterus meets the requirements of IVF. For couples with uterine problems, doctors may take appropriate treatment measures, such as surgery or drug treatment, to improve the success rate of IVF.
Embryonic genetic abnormality
The genetic abnormality of embryo is also one of the common factors of IVF abortion. In vitro culture of IVF embryos, chromosome abnormalities, gene mutations and other problems are prone to occur. These genetic abnormalities of embryos may lead to abnormal development of embryos, and eventually lead to abortion.
In order to reduce the risk of abortion caused by genetic abnormalities of embryos, doctors may conduct chromosome screening before embryo transfer, so as to select healthy embryos for transfer. In addition, the development of assisted reproductive technology also brings hope for solving genetic abnormalities in embryos. For example, the application of gene editing technology can realize the screening and repair of single gene diseases and improve the quality of embryo development.
Maternal age
Maternal age is one of the important factors affecting the risk of IVF abortion. With the increasing age of women, the quality and quantity of eggs will gradually decline, increasing the risk of genetic abnormalities and chromosomal abnormalities of embryos, which will lead to abortion. According to statistics, among women over 35 years old, the proportion of IVF abortion has increased significantly.
For older women, we can consider using young people's eggs for IVF to improve the success rate of pregnancy. In addition, improving living habits, maintaining a healthy diet, moderate exercise, and avoiding excessive tension can also help reduce the risk of miscarriage.
Summary
In vitro abortion may be related to many factors, such as anti embryonic antibody, uterine factors, embryo genetic abnormalities and maternal age. Understanding these common factors can help couples to evaluate and prevent the risk of abortion more rationally when choosing IVF technology. At the same time, doctors' active intervention and treatment can also improve the success rate of pregnancy and bring hope to those couples who are eager to have children.
