What is the reason behind IVF abortion
IVF abortion refers to the process of assisted reproductive technology (ART) in which the embryo naturally stops developing or artificially terminates pregnancy before implantation into the uterus. Although IVF technology has made great breakthroughs in solving the problem of infertility, the abortion rate is still high. There are many reasons behind IVF abortion, including embryo quality, uterine environment, maternal factors and medical procedures.
Embryo quality
The embryo quality of IVF is an important factor affecting the success rate of pregnancy and abortion rate. Poor embryo quality may lead to natural stop of development or complications during pregnancy. One of the main reasons is chromosome abnormality. Older women are more likely to have embryos with chromosomal abnormalities, which may be one of the important reasons for the rise of IVF abortion rate. In addition, the damage of embryos in the process of culture and the decline of embryo survival rate in the process of freezing and thawing also have an impact on the quality of embryos.
In addition to the quality of the embryo itself, the time when the embryo is implanted into the uterus is also an important factor in abortion. If the endometrium is not suitable for embryo implantation, such as insufficient mucus, endometriosis, endometriosis and adenomyosis, the risk of IVF abortion will increase.
In addition, some maternal diseases such as anti phospholipid antibody syndrome may also affect embryo implantation and pregnancy development, increasing the probability of IVF abortion.
Uterine environment
The combing rate of IVF is affected by the uterine environment. The intrauterine environment plays an important role in the growth of embryos and the development of pregnancy. The thickness of endometrium, secretion of glands, blood supply of uterine wall and other factors are closely related to the implantation and development of IVF.
Abnormal uterine morphology may also lead to IVF abortion. Problems such as endometriosis and endometrial myoma will increase the risk of abortion.
At the same time, endometrial immunity is also related to IVF. For example, the abnormal autoimmune function of endometrium leads to the production of endometrial antibodies, which in turn affects embryo implantation and pregnancy.
maternal factors
Maternal age is one of the important factors that affect the rate of IVF abortion. With the increase of age, the quality and quantity of female eggs gradually decline, the chromosome abnormality rate of embryos increases, and the risk of spontaneous termination and abortion also increases. In addition, older women are often accompanied by basic diseases and chronic diseases, such as hypertension and diabetes, which will also increase the possibility of IVF abortion.
Carriers of specific genetic diseases may also increase the risk of IVF abortion. For example, carrying hemophilia gene, thalassemia gene, etc., may lead to complications during pregnancy of the embryo, which may lead to abortion.
Other uterine structural abnormalities, such as hysteromyoma, endometrial polyps, endometriosis and adenomyosis, may also affect the implantation and development of test tube babies and increase the risk of abortion.
Medical operation
Finally, medical procedures also play an important role in IVF abortion rate. The level of operation technology during embryo implantation, the use of narcotic drugs, perioperative monitoring and treatment and other factors may affect the development and maintenance of pregnancy.
In addition, assisted reproductive technology used in IVF may also increase the risk of miscarriage. For example, in the process of IVF, egg collection or embryo transfer may cause a series of complications, which may lead to abortion.
To sum up, there are many reasons for IVF abortion, including embryo quality, uterine environment, maternal factors and medical procedures. Understanding these factors and improving and adjusting related factors can help improve the probability of success of IVF and reduce the risk of abortion.
