Is there a relationship between the frequency of IVF malformations?
Test tube baby is a kind of baby developed through artificial assisted reproduction technology, combining eggs and sperm in the laboratory and cultivating them, and then implanting healthy embryos into the mother's womb. With the development of IVF technology, it has been widely used in the treatment of infertility. However, some people worry that IVF may increase the risk of infant malformation. This article will discuss the frequency of IVF malformations from the aspects of genetic factors, implantation procedures, drug intervention and maternal age.
Genetic factor
The genetic factors of IVF have certain influence on the frequency of infant malformation. First, if one or two parents carry the gene for a genetic disease, the baby may inherit the disease. Secondly, in the process of IVF, gene testing and screening are often carried out to exclude embryos carrying genetic disease genes and reduce the risk of malformation. Therefore, reasonable genetic counseling and screening operations can effectively reduce the occurrence of IVF malformations.
Implantation operation
The operation of IVF embryo implantation will also affect the frequency of infant malformations. The technical level of embryo implantation and doctor's experience are the key factors. Some laboratories and hospitals use advanced implantation technologies, such as single embryo implantation and pulsed implantation, which can improve the implantation rate and survival rate of embryos, thus reducing the risk of malformation. In addition, the selection and quality of implanted embryos also have a certain impact on the occurrence of malformations, so doctors should conduct scientific and reasonable implantation according to the health status and development potential of embryos.
Drug intervention
In the process of IVF, it is often necessary to use some adjuvant drugs to promote ovulation and improve the pregnancy rate. However, the use of these drugs may also cause some side effects, thus increasing the risk of infant malformation. For example, some ovulation promoting drugs may lead to multiple pregnancy, and multiple pregnancy itself will increase the risk of birth defects. Therefore, the dosage of adjuvant drugs should be strictly controlled and medical advice should be observed to minimize the occurrence of malformations.
Maternal age
Maternal age is one of the important factors affecting the frequency of IVF malformations. The increasing age of women is closely related to the increased risk of chromosomal abnormalities and abnormal embryonic development. According to research, babies born to women over 35 years old have a higher risk of chromosomal abnormalities. Therefore, for women aged 35 and above, doctors usually recommend gene testing and screening to exclude embryos with chromosome abnormalities in advance, so as to reduce the incidence of infant malformations.
In conclusion, the frequency of IVF malformation is affected by many factors. Reasonable genetic counseling and screening, advanced implantation technology, scientific and reasonable drug intervention and attention to maternal age can reduce the occurrence of IVF malformation. However, it should be pointed out that there is still a certain risk in the incidence of IVF malformations, so it is necessary to fully understand the relevant medical knowledge before IVF, and fully communicate and negotiate with doctors to make rational decisions.
