How to diagnose IVF malformation?
In vitro fertilization (IVF) refers to the embryo that is cultivated in the laboratory through in vitro fertilization (IVF), and then transferred to the mother's uterus to develop into a baby. Since embryo culture and transfer are carried out in the laboratory, IVF is relatively likely to suffer from malformations. In order to ensure the healthy birth of IVF, doctors have adopted a series of methods to diagnose the abnormalities of IVF.
1. Genetic screening
Genetic screening is a common diagnostic method for early pregnancy and IVF malformations. The risk of chromosomal abnormalities (such as Down's syndrome, Edwards syndrome) and some common genetic diseases can be detected by blood testing of pregnant women. Before IVF transplantation, doctors can detect genetic problems such as chromosomal abnormalities and gene mutations of embryos through hysteroscopy.
In addition to gene testing, doctors can also perform karyotype analysis of embryo nuclei and FISH (fluorescence in situ hybridization) technology testing. These screening methods can effectively help doctors assess the health of embryos and reduce the birth risk of children with malformations.
2. Genetic counseling before embryo implantation
Preimplantation genetic counseling is one of the important steps in IVF malformation diagnosis. Before embryo transfer, the doctor will fully explain the genetic test results and possible risks of the embryo to the couple. They will detail the possible genetic defects and their impact on the development of the child. At the same time, doctors will also discuss treatment options and possible prognosis to help couples make wise decisions.
Genetic counseling can also reveal the risk of genetic disease. For example, if one person in a couple carries the gene of a genetic disease, doctors can recommend them to take specific treatment measures, such as embryonic pathology testing or genetic screening in assisted reproductive technology.
3. Other inspection methods
In addition to genetic screening and genetic counseling, there are other methods for diagnosing IVF malformations.
Ultrasonography is a common diagnostic method, which can help doctors observe the growth and development of infants and find possible organ or structural abnormalities. Through ultrasonic examination, doctors can find fetal malformations as early as possible in order to take appropriate medical measures.
Amniocentesis is a method of examining fetal chromosome structure and genetic diseases. This inspection can detect chromosomal abnormalities and risks of some genetic diseases by obtaining amniotic fluid samples, carrying out fetal chromosome analysis and biochemical indicators detection.
There are some other diagnostic methods, such as fetal magnetic resonance imaging (MRI), amniotic fluid chromosome sequencing and biochemical index examination, which can assist doctors in the diagnosis and monitoring of IVF malformations.
summary
The diagnosis of IVF malformation is a complex and critical process. Through genetic screening, genetic counseling before embryo implantation and other diagnostic methods, doctors can find genetic defects and malformation risks of embryos in advance and help couples make wise decisions. These diagnostic methods have been widely used in some real hospitals, providing an effective guarantee for the healthy birth of test tube babies.
