How high is the incidence of IVF malformation?
With the progress of science and technology and the development of fertility technology, IVF has been increasingly used as a method to solve the problem of infertility. However, many people are worried about the incidence of IVF malformations. This article will elaborate on the incidence of IVF malformation from four aspects.
Background
In vitro fertilization (IVF) is a method of culturing the fertilized eggs in the laboratory and implanting them into the mother's body to give birth. According to the data of the World Health Organization, the success rate of IVF is close to 40%, but the success rate is also affected by many factors. One of the key issues is the incidence of malformations in IVF.
First of all, it needs to be clear that there is no significant difference in the incidence of malformations between IVF and naturally conceived infants. A large number of studies have been carried out in major hospitals and research institutions around the world, and the conclusion is that the incidence of malformations in IVF is comparable to that in naturally conceived infants.
influence factor
The factors influencing the incidence of IVF malformations are very complex, which will be introduced from two aspects below.
1. Individual factors
The incidence of malformations in IVF is closely related to individual factors such as mother's age, chronic diseases and genetic genes. Age is an important risk factor. With the increase of age, women's fertility and embryo quality will decline, thus increasing the risk of malformation. In addition, women with some chronic diseases (such as hypertension, diabetes, etc.) may increase the risk of malformations. Genetics is also a key factor. If there are some genetic diseases in parents or families, it will also increase the probability of IVF malformation.
2. Reproductive technology factors
The operation method of reproductive technology, culture conditions and other factors will also affect the incidence of IVF malformation. In the process of artificial insemination, embryo transfer and other operations, the technical level and experience of the operator have a certain impact on the success rate and deformity rate. In addition, the environmental factors exposed in the process of embryo culture in vitro may also have adverse effects on development, leading to the occurrence of malformations.
How to reduce the incidence of malformations
Although the incidence of malformations in IVF is similar to that of naturally conceived infants, there are still some ways to reduce the probability of malformations.
1. Do a good job of screening in advance
It is very important to have a comprehensive physical examination and genetic counseling in advance. By testing the genes of both spouses, we can assess the risk of suffering from certain genetic diseases, and carry out corresponding counseling and intervention.
2. Select experienced hospitals and doctors
It is very important to select a regular and experienced hospital and doctor for IVF operation. They have higher technical level and operating experience, which can reduce the risk of operational errors and abnormalities.
3. Avoid excessive manipulation of embryos
Excessive manipulation of embryos may lead to embryo defects, thus increasing the risk of malformations. Therefore, excessive manipulation and intervention of embryos should be avoided in the process of operation to maintain the stability of culture conditions.
summary
The incidence of malformations in IVF is similar to that of naturally conceived infants. Individual factors and reproductive technology factors will affect the incidence of malformations. However, measures such as screening in advance, selecting professional hospitals and doctors, and avoiding excessive manipulation of embryos can reduce the probability of malformations. Therefore, for those couples who plan to try IVF, they should fully understand these problems and take appropriate preventive measures while consulting their doctors.
