Selection of down-regulation drugs for IVF
IVF is a method of assisting women to conceive through in vitro fertilization technology. It is an important reproductive choice for couples who cannot conceive naturally. However, some couples may have problems such as ovarian hyperfunction or insufficient ovarian inhibition, which requires drugs to reduce ovarian activity to improve the success rate of IVF. The following will introduce the choice of IVF antidepressant drugs in detail from four aspects.
Progesterone drugs
Progesterone is a commonly used down-regulation drug, which is the main hormone secreted by the corpus luteum in the body and can effectively inhibit the function of the ovary. Progesterone drugs are commonly used for luteal phase support after in vitro fertilization to promote embryo implantation and maintain pregnancy. At present, the common progesterone drugs on the market include Gestalt, luteinizing hormone, etc. These drugs are generally used by injection or oral administration, and the specific dosage needs to be according to the doctor's recommendations.
However, progesterone drugs have certain side effects, which may cause excessive hyperplasia of impurities, breast swelling and pain and other uncomfortable symptoms. Therefore, it is necessary to monitor the progesterone level when using such drugs, closely observe the patient's physical reaction, and adjust the dosage of drugs according to the condition.
Estrogens
Estrogen is one of the important hormones regulating the menstrual cycle of women, which can promote the development and maturation of follicles. In IVF treatment, estrogen drugs can be used to reduce ovarian activity and regulate the speed of follicular development. Common estrogen drugs include Fenliedil, Arbodine, etc. These drugs can be used by injection or orally, and the specific dosage needs to be determined according to personal conditions.
The side effects of estrogen drugs mainly include breast pain, weight gain, etc., and may also increase the risk of thrombosis. Therefore, it is necessary to monitor the use of such drugs to ensure safe use, and adjust the dose in time to reduce the occurrence of side effects.
Gonadotropins
Gonadotropin is an important hormone regulating ovarian function, which can promote the development and maturation of follicles. In IVF treatment, gonadotropins can be used to improve the quantity and quality of follicles and increase the chances of fertilization. Common gonadotropins include human chorionic gonadotropin, follicle stimulating hormone, etc. These drugs are generally used by injection, and the dosage needs to be determined according to individual conditions.
The side effects of gonadotropins mainly include polycystic ovary syndrome, hyperstimulation syndrome, etc., and may also lead to ovarian hyperemia and ovarian cysts. Therefore, close monitoring is needed when using such drugs to avoid side effects.
Doping drugs
Doping drugs are used to increase the success rate of IVF treatment. Doping drugs can stimulate the function of ovary by stimulating the pituitary gland to secrete gonadotropin. Common stimulant drugs include clomiphene, naloxone, etc. These drugs are generally used orally, and the dosage needs to be determined according to the condition of the patient.
The side effects of stimulants may include nausea, vomiting, breast pain, etc., and may also cause polycystic ovary syndrome, ovarian hyperstimulation syndrome, etc. Therefore, it is necessary to closely monitor the use of such drugs and adjust the dose to reduce the occurrence of side effects.
Summary
The choice of IVF lowering drugs depends on the patient's specific condition and needs. Progesterone drugs, estrogen drugs, gonadotropins and stimulants are common drugs for lowering the tone. However, when using these drugs, it is necessary to closely monitor the patient's physical reaction and adjust the dose according to the situation to ensure the safety and effectiveness of IVF treatment.
