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What are the drugs for IVF lowering?

What are the drugs for IVF lowering?



Options for IVF down-regulation drugs

IVF downregulation is an assisted reproductive technology, which promotes the development of follicles and ovulation and increases the chance of pregnancy through drugs that regulate the function of women's ovaries. In the process of IVF, doctors may use different drugs to achieve the goal of lowering the tone. Next, we will introduce the drug options of IVF from four aspects: ovulation promoting agents, antiandrogens, antibiotics and antiallergic drugs.

Ovulatory stimulant

Ovulation promoting agents are mainly used to promote ovarian development and follicle discharge of mature eggs. Common ovulation promoting agents include: 1. Human chorionic gonadotropin (hCG): hCG can simulate the luteinizing hormone produced by the human body, promote the follicle to discharge mature eggs, and make the corpus luteum to secrete progesterone, maintain the stability of the endometrium, and improve the success rate of implantation. 2. Gonadotropin (FSH): FSH is a drug commonly used in the process of in vitro fertilization (IVF), which can promote ovarian development and stimulate the growth and development of follicles. FSH usually needs to be injected continuously at the ideal concentration for a period of time to obtain the best therapeutic effect. 3. Luteinizing hormone releasing hormone (GnRH) agonists: GnRH agonists can reduce non-specific corpus luteum rupture, control the cycle of test tube babies and improve the pregnancy rate by inhibiting the pituitary secretion of follicle stimulating hormone (FSH and LH).

Antiandrogen

Antiandrogens are used to block the adverse effects of androgens on ovaries, avoid premature follicle rupture and luteal formation, and thus increase the chances of fertilized eggs implantation. Common antiandrogens include: 1. Flutamide: It is a non steroidal antiandrogen, which can effectively resist the adverse effects of male hormones on follicular development. 2. Estrogen antagonists (Aromatase Inhibitors): estrogen antagonists can prevent the transformation of androgen into estrogen, thereby reducing the level of estrogen, reducing the sensitivity of the ovary to androgen, and promoting the growth and development of follicles.

antibiotic

In the process of IVF, sometimes doctors may use some antibiotics to prevent or treat possible infections. Common antibiotics include: 1. Azithromycin: Azithromycin is a broad-spectrum antibiotic, which is commonly used to prevent Gram negative bacterial infection in test tube infants. 2. Cefalexin: Cefalexin is a kind of β- Lactam antibiotics are commonly used to prevent and treat bacterial infection in IVF surgery.

Antiallergic drug

Some IVF patients may be allergic to some ovulation promoting drugs, resulting in allergic reactions. When these drugs need to be used, doctors may recommend that patients use anti allergy drugs for prevention before treatment. Common anti allergic drugs include: 1. Loratadine: Loratadine is a non sedative antihistamine, commonly used to treat allergic rhinitis, allergic dermatitis and other allergic diseases. 2. Ketotifen: It is an antihistamine and can also be used to prevent allergic reactions in test tube babies. To sum up, the drug options for IVF down-regulation include ovulation promoting agents, antiandrogens, antibiotics and antiallergic drugs. Doctors will select appropriate drugs according to the specific conditions and needs of patients, and closely monitor and adjust the drug dosage during the treatment process to improve the success rate of IVF.
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