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What are the similarities and differences between the first generation and the second generation of IVF?



Fertility process and technology development of the first and second generation of IVF

In vitro fertilization (IVF) refers to the fertilization and breeding of babies in the laboratory through in vitro fertilization (IVF). Since the successful implementation of IVF technology in 1978, after years of development and improvement, the concept of first generation and second generation IVF has emerged. The first generation of IVF refers to the period since the first implementation of IVF technology, while the second generation of IVF refers to the latest generation after continuous improvement of IVF technology with the continuous progress and innovation of technology.

 What are the similarities and differences between the first generation and the second generation of IVF?

1. Improvement of fertility success rate

In the first generation of IVF, IVF technology is still in its infancy, and the fertility success rate is relatively low. The success rate of fertilized eggs and embryo transfer is not high, and few women can successfully conceive and bear. However, during the second generation of IVF, after a long period of technical improvement and progress, the fertility success rate has been significantly improved. The advanced equipment and technology adopted by modern hospitals such as Beijing Antai Hospital has made the success rate of IVF reach a high level. Many infertile couples can successfully conceive and give birth to healthy babies through this technology.

For example, the second generation of IVF adopts an auxiliary incubation device, which can simulate the intrauterine environment and increase the success rate of embryo capture and implantation. In addition, it is possible to use genetic techniques to select the sex of the fertilized egg. The improvement of fertility success rate is one of the key differences between the second generation and the first generation of IVF.

2. Personalized medical treatment

During the generation of IVF, the treatment plan was relatively single, and the concept of personalized medical treatment was lacking. Generally, women will accept the standardized IVF process and lack individualized targeted treatment. However, with the development of IVF technology and the arrival of the second generation, doctors are paying more and more attention to developing personalized treatment plans according to the specific conditions of different couples.

Modern hospitals, such as the Obstetrics and Gynecology Hospital affiliated to Fudan University, have developed more sophisticated IVF programs by comprehensively considering the age, physical condition, reproductive system problems and other factors of the couple, which has improved the fertility success rate of infants. The introduction of personalized medicine is another important difference between the first generation and the second generation of IVF.

3. Application of genetic technology

The second generation of IVF adopts more genetic technology, so that more accurate detection and screening can be carried out before embryo transfer. These genetic technologies include but are not limited to breeding technology, embryo chromosome abnormality screening, single gene disease screening, genetic disease gene detection, etc.

The application of these technologies enables the second generation of IVF to select healthy fertilized eggs more accurately for transplantation to avoid genetic diseases. At the same time, for older women, genetic technology can also help screen embryos with chromosomal abnormalities, improve the success rate of pregnancy and reduce the risk of abortion.

4. Increased social acceptance

During the generation of IVF, IVF technology was regarded as a new thing, and the society had relatively low acceptance of it, even there were many negative views and prejudices. However, with the passage of time and the gradual maturity of the second generation technology of IVF, the acceptance of IVF in society has increased significantly.

More and more couples choose IVF technology, on the one hand, because of the improvement of its success rate, on the other hand, because the society's recognition of IVF is increasing. While helping infertile couples realize their dreams, the second generation of IVF also promotes the society's attention and understanding of infertility.

Summary

There are obvious differences between the first generation and the second generation of IVF in fertility success rate, personalized medical care, genetic technology and social acceptance. The second generation of IVF has made great progress and improvement in these aspects, providing more hope and options for infertile couples. With the continuous progress of science and technology, it is believed that IVF technology will continue to develop, providing support for more couples to realize their reproductive dreams.

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