Low success rate of IVF
In vitro fertilization (IVF) refers to the reproductive technology that fertilizes the patient's eggs and sperm in vitro, cultivates the fertilized eggs to the blastocyst stage, and then transfers the blastocysts back to the patient's uterus to achieve the purpose of pregnancy and delivery. Although the development of IVF technology has brought hope to infertile patients, there are still some low success rates.
1. Main reasons for low success rate
One of the main reasons for the low success rate of IVF technology is the quality and quantity of eggs. In women, only a few eggs can develop to maturity every month, while multiple eggs need to be collected during IVF, which increases the possibility of abnormal development and abortion. In addition, the quality of eggs will also be affected by age, lifestyle, heredity and other factors.
Another reason for the low success rate of IVF is endometrial problems. The endometrium is the environment for embryo implantation. If the endometrium is too thick or too thin, it will affect embryo implantation and development. Moreover, endometrial problems are often related to immune dysfunction, abnormal hormone secretion and other factors.
In addition, the quantity and quality of sperm are also one of the reasons for the low success rate of IVF. The low number, low vitality or abnormal morphology of sperm in male patients will reduce the success rate of fertilization. The IVF technology has high requirements for the quantity and quality of sperm, so it will become an important factor restricting its success rate.
2. Problem of premature egg failure
The problem of egg quality and quantity is particularly prominent in IVF. With the growth of age, women's ovarian function gradually weakens, and the number and quality of eggs will also decline. Especially in women over 35 years old, ovarian function decline will be more obvious, and the success rate will also be significantly reduced. Even with the help of assisted reproductive technology, the success rate of these patients is still relatively low.
The current solution to the problem of premature egg failure is to freeze eggs. When women are young, they can freeze their eggs for future use in IVF. However, the success rate of frozen eggs is also affected by many factors, including egg quality, damage during freezing and thawing, etc. Therefore, this method cannot completely solve the problem of premature egg failure for older women.
3. Risk of multi embryo pregnancy
In order to increase the success rate of IVF, doctors sometimes transplant multiple blastocysts back to the patient's uterus. However, this also leads to the risk of multiple embryo pregnancies. Multiple embryo pregnancy is easy to cause a series of complications, such as premature delivery, placental insufficiency, fetal growth retardation, etc. These complications have adverse effects on the health of mothers and fetuses, increasing the risk of pregnant women and newborns.
Therefore, doctors need to weigh the relationship between success rate and multiple embryo pregnancy risk when deciding the number of embryos to be transferred, and make reasonable decisions. At present, some hospitals are also constantly improving the transfer technology to reduce the occurrence of multiple embryo pregnancy.
4. Psychological pressure and economic burden
The psychological pressure and financial burden during IVF is also a major disadvantage of low success rate. IVF is a long-term and expensive process for patients. Patients need to go through many steps such as ovarian stimulation, egg retrieval, embryo culture, transplantation, etc. These processes not only need financial support, but also bear physical and psychological pain and pressure.
In addition, the success of IVF depends not only on the technical level, but also on the lifestyle of patients, genetic factors, environment and other factors. Therefore, for some infertile patients, it may take many attempts to succeed, which further increases their psychological burden.
Summary
In conclusion, although IVF technology has brought hope to infertile patients, it still has the disadvantage of low success rate. The main reasons include egg quality and quantity, endometrium, sperm quantity and quality. In addition, premature egg failure, multiple embryo pregnancy risk, psychological pressure and economic burden are also important factors leading to low success rate. Therefore, when choosing IVF technology, patients need to fully understand its advantages and disadvantages, and fully communicate and make decisions with doctors. At the same time, medical institutions should also constantly improve their technical level to improve the success rate of IVF.
