Requirements of IVF technology on embryo quality
IVF technology is an important breakthrough in the field of reproductive medicine, and its success is closely related to the quality of embryos. The quality of IVF embryos directly affects the success rate of transfer and the healthy development of subsequent pregnancy. In order to ensure the success of IVF technology and reduce the risk of congenital diseases, the quality of embryos must meet certain requirements. The quality requirements of IVF embryos are described in detail in the following four aspects.
1. Whether the chromosome is normal
Chromosome abnormality is one of the main factors leading to embryo implantation failure and fetal malformation. In IVF technology, whether the embryo's chromosome is normal or not is regarded as an important indicator to measure its quality. At present, the commonly used chromosome screening methods include centromere chromosome research, karyotype analysis and submicron chromosome CGH. Through these technologies, embryos with abnormal chromosomes can be found as soon as possible, avoiding their transfer, and improving the acquisition rate of healthy embryos.
In addition, in order to further improve the success rate of IVF, some hospitals also use PGS (Embryo Chromosome Screening) technology, that is, to screen embryos with abnormal chromosomes through whole chromosome screening, so as to avoid transplanting them into the maternal uterus.
2. The commercialization of embryos
The development of IVF technology has brought new hope for human reproduction, but there have also been some moral and ethical problems. Among them, the commercialization of embryos has attracted much attention. The quality requirements of embryos are not only to increase the success rate of transplantation, but also to follow the ethical and moral principles, to avoid excessive screening and selection of embryos, and to avoid commercial use of embryos.
In order to solve this problem, some countries and regions have formulated strict laws and moral standards, which stipulate how to screen and use embryos. Doctors and scientists must strictly abide by these regulations, ensure the reasonable and fair use of IVF technology, and set reasonable requirements for embryo quality.
3. Ensure the healthy development of embryos
In IVF technology, the requirements of embryo quality not only include whether the chromosome is normal or not, but also need to ensure the healthy development of the embryo. This requires observation and evaluation of the embryo's morphology, cell number, cell division speed, etc.
Some hospitals use equipment such as embryo incubators to provide suitable environmental conditions for embryos to promote their healthy development. Doctors will evaluate the embryos regularly, and select high-quality embryos for transplantation according to the internal and external morphology, cell development, development speed and other indicators of the embryos.
4. Genetic disease screening
Screening for genetic diseases is also an important aspect of IVF embryo quality. Some serious genetic diseases, such as Down's syndrome and cystic fibrosis, will seriously affect the life and health of infants. In IVF technology, genetic disease screening of embryos can help doctors select embryos carrying normal genes for transfer.
Genetic disease screening is usually accomplished by taking embryos for gene testing. The hospital will analyze the genes of both spouses in advance to determine the possibility of carrying risk genes. Then, in the process of IVF, genetic disease screening technology is used to detect the genes of embryos, so as to screen the embryos carrying normal genes for transplantation.
summary
The success of IVF technology is closely related to embryo quality. Whether the chromosome of the embryo is normal, the commercialization of the embryo, the healthy development of the embryo and the screening of genetic diseases are all important factors for the requirements of embryo quality. Following ethical and moral principles, ensuring the healthy development of embryos, and conducting reasonable genetic disease screening can improve the success rate of IVF and reduce the risk of congenital diseases.
