Causes of premature birth of twins in test tube infants
With the development of IVF technology, many infertile couples have realized their dream of having children, and the birth rate of twins has gradually increased. However, compared with naturally conceived twins, IVF twins are more likely to give birth prematurely. This phenomenon has aroused widespread concern in the medical community. This article will discuss the reasons why IVF twins are prone to premature delivery from many aspects.
1. Increased risk of multiple pregnancy
IVF technology usually implants multiple fertilized eggs into the mother to increase the probability of successful pregnancy. However, this has also led to a significant increase in the risk of multiple pregnancies. For twins, competition between fetuses may occur during embryonic development, resulting in slow growth and poor development of some fetuses. At the same time, the burden of multiple pregnancy on the mother is also greater, which increases the risk of premature delivery.
In addition, multiple pregnancy will also lead to uneven expansion of uterine muscle layer and decreased uterine contractility, thus affecting placental perfusion and fetal blood supply. The growth and development of the twins have brought adverse effects, further increasing the incidence of premature delivery.
2. Unstable intrauterine environment
The pregnancy process of IVF twins is very different from that of natural pregnancy. In IVF technology, the fertilized egg is cultured in the laboratory for a period of time before being implanted into the mother's uterus. During this process, the internal environment of the uterus has changed, which may cause inflammation in the endometrium and affect the implantation of embryos and the stability of pregnancy.
In addition, the assisted reproductive technology drugs used in IVF technology may also have an impact on the intrauterine environment. These drugs can reduce uterine contractility and increase the risk of premature delivery while promoting ovarian development. In addition, the influence of drugs on uterine blood flow may also lead to placental dysfunction, which may lead to premature delivery.
3. Inadequate management of maternity care
As the pregnancy and delivery process of IVF twins is more complicated, more rigorous medical management is needed. However, there is still insufficient management of maternity care. First of all, due to the insufficient popularity of IVF technology, some hospitals lack relevant experience and expertise to provide the best maternal health care support.
Secondly, because the whole process monitoring of IVF is long, the demand for medical resources is high. In some hospitals, due to the shortage or uneven distribution of medical resources, there are deficiencies in monitoring, diagnosis and treatment during pregnancy and childbirth. These adverse factors may increase the risk of premature delivery.
4. Impact of embryo implantation technology
The process of embryo implantation in IVF technology may also affect the premature delivery rate of twins. First of all, the location and mode of embryo implantation may have an impact on the development of embryos and the intrauterine environment. Inappropriate implantation location and mode may lead to unstable intrauterine environment and increase the risk of premature delivery.
In addition, the process of embryo implantation may lead to damage of endometrial blood vessels, thus affecting embryo nutrition and oxygen supply. The growth and development of the twins may have a negative impact, increasing the risk of premature delivery.
Summary
The reasons why IVF twins are prone to premature birth can be analyzed from many aspects. First, the increased risk of multiple pregnancies leads to premature delivery. Secondly, the unstable intrauterine environment and inadequate medical management of pregnancy and childbirth will also increase the risk of premature delivery. Finally, the impact of embryo implantation technology may also have an impact on the premature delivery rate of twins. Further strengthening the research on pregnancy and birth management and related technologies of test tube twins will help reduce the risk of premature delivery and improve the healthy birth rate of test tube twins.
