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Why is the failure rate of IVF high?

Why is the failure rate of IVF high?

In vitro fertilization and embryo transfer (IVF and ET) is an assisted reproductive technology, which is used to solve the problem of infertility caused by various factors. However, although IVF technology has made great breakthroughs in the field of modern medicine, the failure rate of IVF is still high. This article will analyze in detail why IVF has a high failure rate from four aspects.

Aspect 1: female factors

The failure rate of IVF is closely related to female factors. First, age is one of the most important factors for women. With the growth of women's age, the ovarian function gradually declines, and the quality and quantity of eggs will become worse, which will lead to the reduction of the success rate of IVF. Secondly, women have certain reproductive system diseases, such as endometriosis, hysteromyoma, etc. These problems may lead to the failure of IVF. In addition, the imbalance of hormone levels in women will also affect the success rate of IVF. The reason may be the abnormal ovarian function caused by endocrine disorder, which affects the quality and quantity of eggs and increases the risk of IVF failure.

Aspect 2: Male factors

Although the IVF technology is mainly designed for female infertility, male factors will also have an important impact on the results of IVF. Poor semen quality of men will directly affect the effect of fertilization, and semen quality is affected by many factors, such as sexual habits, environmental factors and genetic factors. If the quality of male semen is poor, the failure rate of IVF will increase.

Aspect 3: Embryo quality

Another important reason for the high failure rate of IVF is the quality of embryos. Sometimes, when a certain number of eggs are obtained, the number of embryos eventually developed is not much. This is due to the influence of ovarian hormones or other treatment or operational factors. In addition, the quality of embryos will also be affected by genetic factors or potential genetic diseases. Therefore, if the embryo quality is not good, even if the successful transfer is difficult to achieve a successful pregnancy.

Aspect 4: Other factors

In addition to female factors, male factors and embryo quality, there are other factors that can also lead to the failure of IVF. For example, the immune system reaction in patients may affect embryo implantation. This immune system reaction may regard the embryo as a foreign substance to attack, thus leading to pregnancy failure. In addition, surgical techniques and operator experience also have a certain impact on the success rate of IVF.

summary

To sum up, the high failure rate of IVF is mainly caused by female factors, male factors, embryo quality and other factors. Through further research and continuous improvement of technology, it is believed that the success rate of IVF technology will gradually increase. At the same time, patients should be more careful when choosing hospitals and doctors, and choose regular medical institutions and experienced doctors for IVF treatment, so as to improve the success rate and increase the birth rate of babies.
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