How does the duration of DHEA affect the effect of IVF?
With the progress of science and technology, IVF has become one of the ways for many infertile couples to achieve their reproductive aspirations. During IVF, women are often advised to use dehydroepiandrosterone (DHEA) to improve ovarian function. However, how does the duration of DHEA affect the effect of IVF? This article will elaborate on personalized treatment, follicle quality, fertilization rate and pregnancy.
personal therapy
IVF is a highly personalized treatment method, and the situation of each patient may be different. Therefore, the duration of DHEA varies from person to person. Generally, 3-6 months of DHEA supplementary treatment and 1-3 months of high-quality egg cultivation are recommended. The duration of individualized treatment can be determined according to the patient's ovarian reserve, egg quality, treatment response and other factors.
For older women with reduced ovarian reserve, longer use of DHEA may be more beneficial. A study showed that after 12 months of DHEA treatment, the egg quality and pregnancy rate of women over 40 years old were significantly improved. For young women with good ovarian reserve, a shorter duration of DHEA may be enough.
Therefore, according to individual differences and doctors' suggestions, it is very important to choose a suitable DHEA use duration.
Follicle quality
There is a certain correlation between the duration of DHEA use and follicular quality. The follicle is an important organization in the female body responsible for ovulation and pregnancy. The quality of the egg directly affects the success rate of IVF.
A study explored the impact of DHEA treatment and found that the quality of eggs produced by women using DHEA during ovulation was better, and the quality of fertilization and embryonic development was also higher. In addition, DHEA can also improve ovarian function and increase the number and size of follicles.
Therefore, longer use of DHEA may produce better follicle quality, thus improving the success rate of IVF.
Fertilization rate
Fertilization is a key step in the process of IVF and one of the important factors that determine the success rate. The duration of DHEA may also affect the fertilization rate.
Research shows that the fertilization rate of women using DHEA is relatively high during IVF. DHEA can promote the development and maturation of eggs and increase the possibility of fertilization. In addition, longer use of DHEA can also increase the number of eggs and further improve the fertilization rate.
Therefore, longer use of DHEA may lead to higher fertilization rate, which is conducive to the success of IVF.
Probability of pregnancy
The ultimate goal of IVF is to have a successful pregnancy and a healthy baby. The duration of DHEA use also has a certain impact on the probability of pregnancy.
A study found that women's pregnancy rate increased significantly after long-term treatment with DHEA. Especially for older women with decreased ovarian reserve, longer use of DHEA can significantly increase the probability of pregnancy.
Therefore, longer use of DHEA can increase the probability of successful pregnancy of IVF and help infertile couples achieve their fertility aspirations.
summary
In conclusion, the duration of DHEA has a certain impact on the effect of IVF. The duration of personalized treatment, follicle quality, fertilization rate and pregnancy probability may be affected by the duration of DHEA. Longer use of DHEA may result in better follicle quality, higher fertilization rate and pregnancy probability, especially for older women with reduced ovarian reserve. However, individual differences and doctors' suggestions also need to be taken into account, and everyone should choose the appropriate use duration of DHEA according to their own conditions.
