Risk and contraindication of IVF in patients with big three positive
IVF is a kind of assisted reproductive technology, which can help couples who cannot conceive naturally realize their desire to have children. However, there may be some risks and contraindications in IVF for patients with big three positive. This article will elaborate on this from four aspects.
1. Pregnancy risk
Major three positive patients include hepatitis B major three positive, hepatitis C major three positive and syphilis major three positive. These diseases may have an impact on the fetus and mother during pregnancy. For example, hepatitis B virus can be transmitted to the fetus via the placenta, leading to vertical transmission of infection. If hepatitis B virus infection occurs in the early pregnancy, it may increase the risk of fetal dysplasia and premature delivery. In addition, patients with hepatitis B and C may experience changes in liver function and increase in virus replication rate during pregnancy, further increasing the risk of complications during pregnancy.
Therefore, test tube baby may not be an ideal choice for patients with big three positive, especially those found in early pregnancy. Before considering IVF, patients should receive adequate consultation and medical evaluation, and carry out corresponding disease treatment under the guidance of professional team to minimize the risk of pregnancy.
2. Risk of infection transmission
The diseases of patients with Big Three Yang are infectious, especially hepatitis B and C. In the process of IVF, multiple egg retrieval and embryo transfer may be involved, and these operations may increase the risk of virus transmission.
Therefore, in the process of IVF, strict infection control measures need to be taken to ensure that medical staff and other patients are free from the risk of infection. Including but not limited to the use of disposable instruments, disinfection and protection measures, early screening and treatment, etc. In addition, patients with Big Three Positive also need to pay attention to personal hygiene in their personal life to avoid the spread and infection of the virus.
3. Selection of embryo implantation
The choice of embryo implantation is an important consideration for patients with big three positive. For example, HBV negative embryos should be given priority in the selection of embryos for patients with hepatitis B and three positives to reduce the risk of fetal infection. Therefore, before IVF, patients need to undergo embryonic genetic screening to determine whether the embryo carries the corresponding virus.
In addition, patients with big three positive should also closely monitor the virus replication rate and changes in liver function indicators during IVF to ensure the timing of embryo implantation and the safety of operation.
4. Disease treatment and monitoring
Big three positive patients need to receive disease treatment and monitoring before undergoing IVF. For example, hepatitis B patients can use antiviral drugs or vaccines to control virus replication and protect liver function, thereby reducing the risk of pregnancy. Patients with hepatitis C can also receive antiviral treatment to control virus replication and liver function recovery.
In the process of IVF, patients with Big Three Positive should closely monitor the virus replication rate, liver function indicators, pregnancy related indicators, etc., and communicate with the medical team at any time and make regular follow-up visits.
Summary
IVF for patients with Big Three Positive may face pregnancy risks, infection transmission risks, challenges in embryo implantation selection, and requirements for disease treatment and monitoring. Therefore, before deciding to carry out IVF, patients with Big Three Positive should fully understand the risks and contraindications, accept the guidance and assessment of the professional team, and actively treat and control diseases to ensure the safety and success rate of IVF process.
