Angel test tube baby: selection of high-quality embryos
The development of IVF technology provides new opportunities for infertile couples to realize their reproductive dreams. In the process of IVF, selecting high-quality embryos is a very important step. This article will elaborate on how to select high-quality embryos from four aspects.
Evaluation of embryo appearance
The appearance evaluation of embryos is the first step to select high-quality embryos. In the process of culture, the embryo should have uniform cell division and clear cell morphology. First, the cell division of the embryo should be very uniform, and the number of cells should not be significantly reduced or increased. Secondly, the cell morphology of the embryo should be normal without obvious abnormalities, such as uneven nuclear size. By observing the appearance of embryos, high-quality embryos with development potential can be preliminarily screened.
At the same time, some hospitals also use the embryo time conversion method to evaluate the embryo development speed. According to the cell division of the embryo, the age of the embryo can be estimated, and then the normal development of the embryo can be judged. Generally speaking, the faster the embryo's cell division speed is, the greater its development potential is.
Gene testing
Gene detection is an advanced technology for selecting high-quality embryos. Through gene testing, we can evaluate whether the embryo carries certain genetic diseases or gene mutations. This technology can help couples avoid transferring embryos with genetic diseases into the uterus, thus reducing the possibility of giving birth to babies at risk of genetic diseases.
At present, the commonly used gene detection methods include PCR technology SNP chip detection and whole genome sequencing. These methods can comprehensively test the genome of embryos, help determine whether there is a risk of certain diseases, and thus select healthy and high-quality embryos.
Chromosome analysis
Chromosome abnormality is one of the main reasons for embryo development failure. Therefore, chromosome analysis is one of the important means to select high-quality embryos. Chromosome analysis can be used to detect whether the embryo has abnormal chromosome number and structure, such as Down's syndrome and Edwards syndrome.
Common chromosome analysis methods include FISH CGH technology and SNP chip technology. These techniques can accurately detect the number and structure of chromosomes in embryos and help to select high-quality embryos with normal chromosomes.
Embryo quality assessment
Embryo quality assessment is the result of comprehensive consideration of embryo appearance, gene detection, chromosome analysis and other factors. In the embryo quality assessment, the hospital will classify embryos according to certain standards, such as A Class B Class C, etc. Grade A embryos are usually the most promising and suitable for transplantation, while Grade C embryos have relatively low development potential.
In order to select high-quality embryos, it is not only necessary to consider factors such as embryo appearance, gene detection and chromosome analysis, but also need to combine their own specific conditions and doctors' suggestions. Only by comprehensively considering these factors can we select the most suitable embryo and increase the chance of success of IVF.
Summary
Selecting high-quality embryos is a key step in the process of IVF. The evaluation of embryo appearance, gene detection, chromosome analysis and embryo quality evaluation are all important bases for selecting high-quality embryos. Different hospitals may adopt different evaluation methods and standards, so their technical level and professional experience should also be considered when selecting hospitals. Finally, through scientific choices, couples can increase the probability of IVF success and realize their reproductive dreams.
