1. Definition and principle of IVF
IVF is one of the assisted reproductive technologies, also known as in vitro fertilization embryo transfer (IVF-ET). It is a way to help couples who cannot conceive naturally achieve fertility. The basic principle is to combine the woman's egg with the man's sperm in vitro, cultivate the embryo, and then transfer the embryo to the woman's uterus to achieve the purpose of pregnancy.
In IVF treatment, a series of drugs and treatment methods are involved. The following four aspects will be described in detail from the use of drugs, operation and application of auxiliary technology.
2. Drugs used
In the process of IVF treatment, the following drugs are often used:
a) Ovulation promoting drugs: increase the number of eggs by promoting ovarian ovulation. Common ovulatory drugs include human chorionic gonadotropin (hCG), gonadotropin (FSH), etc.
b) Anti estrogen drugs: prevent the early rupture and excretion of follicles in the ovary, thus prolonging the growth process of the egg. The commonly used anti estrogen drugs include Gaudalu injection, Amulin injection, etc.
c) Progesterone drugs: used to maintain the stability of endometrium and embryonic development. The commonly used progesterone drugs include androne, levonorgestrel, etc.
3. Operation
The main surgical procedures in IVF treatment include the following steps:
a) Ovarian stimulation: promote ovarian development and increase the number of eggs by using ovulation promoting drugs.
b) Egg collection: at an appropriate time, puncture the ovarian cyst under the guidance of ultrasound to collect eggs.
c) Combination of sperm and egg: combine the collected egg with the sperm with high vitality for in vitro fertilization.
d) Embryo culture: culture the combined embryos in a specific culture medium for a suitable culture time.
e) Embryo transfer: After a certain period of embryo culture, the embryo is transferred to the woman's uterus.
4. Application of auxiliary technology
In order to improve the success rate of IVF, the following assistive technologies are often used:
a) Frozen embryo transfer: The surplus embryos are frozen and stored, and then thawed when necessary for embryo transfer.
b) Embryo chromosome screening: through chromosome screening of embryos, select embryos with normal chromosomes for transplantation to reduce the risk of abortion caused by chromosome abnormalities.
c) Gene testing: In order to screen genetic diseases, we can carry out gene testing on embryos, screen embryos carrying genetic disease genes, and improve the success rate of embryo transfer.
To sum up, ovulation promoting drugs, anti estrogen drugs and progesterone drugs are often used in IVF treatment. Operation procedures include ovarian stimulation, egg collection, combination of sperm and egg, embryo culture and embryo transfer. Auxiliary technologies mainly include frozen embryo transfer, embryo chromosome screening and gene detection. The selection and application of these drugs and treatments can greatly improve the success rate of IVF and help couples who cannot conceive naturally achieve their fertility aspirations.
