Requirements for the third generation IVF
With the continuous development of medical technology, IVF technology has gradually entered the third generation. The third generation of IVF is more sophisticated in operation and has a higher success rate than the previous two generations. However, in order to successfully carry out the third generation of IVF, certain conditions need to be met. The following is a detailed description of genetic disease screening, female age, uterine health and male sperm quality.
Genetic disease screening
If a couple who are going to have the third generation of IVF has a family with hereditary disease, it is recommended to do relevant gene testing and genetic counseling before IVF. This is because genetic diseases may be passed on to the next generation. If the test results show that there is a gene mutation of a serious genetic disease, couples can choose to carry out gene screening and embryo selection to reduce the risk of disease in the next generation.
In addition, the third generation IVF technology can also realize PGS (embryonic chromosome screening) and PGD (single gene disease screening) and other technologies, help couples screen and exclude embryos with abnormal genes, and increase the success rate of IVF.
Female age
The age of women has a great influence on the success rate of IVF. The success rate of the third generation IVF for women under 35 years of age is relatively high, generally more than 40%. However, with the growth of age, women's reproductive function will gradually decline, the quality of eggs will also weaken, and the success rate will decline. Therefore, for women over 35 years old, it is recommended to conduct a comprehensive physical examination before IVF to assess ovarian reserve and egg quality.
If the egg quality is poor, we can consider using the technology, that is, using donated eggs for the third generation of IVF. At the same time, if the ovarian function declines significantly, you can also choose or use donated eggs and sperm.
Uterine health
Uterine health is another important condition for the third generation of IVF. The thickness of endometrium and blood supply play an important role in embryo implantation and development. If the female uterus has structural abnormalities, thin endometrium, insufficient blood flow or other diseases that affect the health of the uterus, the success rate of IVF will be affected.
Therefore, before the third generation of IVF, it is recommended that women should have a detailed examination of the uterus. If necessary, they can have hysteroscopy or endometrial relaxation to improve the implantation and development environment of embryos.
Male sperm quality
Male sperm quality is also one of the important factors affecting the success of the third generation IVF. Sperm quality includes sperm quantity, motility, morphology, etc. If the number of male sperm is too small, the vitality is low or the morphology is abnormal, it will affect the quality and success rate of the embryo.
Therefore, before couples choose the third generation IVF, men need to conduct sperm quality inspection, such as routine semen inspection, sperm motility inspection, etc. If the sperm quality is found to be poor, ICSI technology can be used, that is, single sperm can be injected into the egg through microinjection to increase the fertilization rate.
To sum up, the success of the third generation of IVF needs to meet the conditions of genetic disease screening, female age, uterine health and male sperm quality. Only on the basis of meeting these conditions can we improve the success rate of IVF and help more couples realize their dreams of healthy babies.
