Application of cyclosporine in test tube infants
Test tube baby is a kind of assisted reproductive technology. For those couples who cannot conceive naturally, it is a way to achieve their reproductive aspirations. Cyclosporine is an immunosuppressant, and its application methods in IVF include the following aspects:
1. Immune suppression for preparing patients
In the process of IVF, the patient's immune system may have an immune response to the embryo, leading to embryo implantation failure. In order to reduce the immune response, doctors will give patients immunosuppressants such as cyclosporine before IVF to inhibit the attack of the immune system on the embryo. Cyclosporine can inhibit the activity of T cells, reduce the immune response, and improve the success rate of test tube babies.
The method of use is as follows:
Step 1: A few months before the IVF cycle begins, the doctor will prescribe cyclosporine to the patient and determine the dose according to the specific situation of the patient.
Step 2: According to the doctor's instructions, patients take cyclosporine on time every day, and pay close attention to the side effects of the drug.
Step 3: A few weeks before the start of the IVF cycle, patients need to have relevant examinations and adjust the dose of cyclosporine according to the examination results.
2. Immune adjustment for egg donors
In some cases, since the donated eggs come from different individuals, the patient's immune system may have an immune response to the eggs. In order to reduce the immune response, doctors will give immunosuppressants such as cyclosporine to donors before IVF to reduce the risk of immune rejection.
The method of use is as follows:
Step 1: Doctors will evaluate the donor's immunity to determine whether immunosuppressive drugs are needed.
Step 2: During the donation process, doctors will give immunosuppressants such as cyclosporine according to the evaluation results, and determine the dose according to the specific circumstances of the donor.
Step 3: Donors need to take immunosuppressants on time and receive monitoring and adjustment from doctors during the donation process.
3. For immunosuppression after embryo transfer
In the process of IVF embryo transfer, the patient's immune system may attack the embryo, leading to transfer failure. In order to reduce the immune response, doctors will give immunosuppressants such as cyclosporine to patients after embryo transfer to protect the safe implantation and development of embryos.
The method of use is as follows:
Step 1: A few days before embryo transfer, the doctor will prescribe cyclosporine medicine to the patient, and determine the dose according to the specific situation of the patient.
Step 2: Patients need to take cyclosporine on time every day according to the doctor's instructions, and pay close attention to the side effects of the drug.
Step 3: A few weeks after embryo transfer, patients need to undergo relevant examinations and adjust the dose of cyclosporine according to the examination results.
4. Precautions
Although the application of cyclosporine in IVF can improve the success rate, there are still some risks and side effects. When using cyclosporine, patients should pay attention to the following matters:
Step 1: Before taking any medicine, the patient needs to consult the doctor in detail to understand the effect, dosage and common side effects of the medicine.
Step 2: During the period of taking medicine, the patient needs to visit again regularly, and the doctor will adjust the drug dose according to the specific situation of the patient.
Step 3: When using cyclosporine, patients should avoid contact with the source of infection, enhance their own immunity, and minimize the risk of infection.
summary
The application of cyclosporine in IVF mainly includes immunosuppression for preparing patients, immunomodulation for egg donors and immunosuppression after embryo transfer. Through reasonable use of cyclosporine, the success rate of IVF can be improved. However, patients should strictly follow the guidance of doctors when using cyclosporine, and pay attention to the side effects and precautions of drugs.
