How does the HCG value of IVF judge the normal development of embryos?
IVF refers to the process of inserting the fertilized egg into the uterus for pregnancy through assisted reproductive technology. In the process of IVF, HCG (human chorionic gonadotropin) is an important indicator, which can be used to judge whether the embryo develops normally. This article will elaborate on embryo implantation, HCG value detection time, normal range of HCG value and possible reasons for abnormal values.
Embryo implantation
Embryo implantation refers to the process of fertilized eggs adhering to and embedding into the endometrium in the uterus. Successful embryo implantation is one of the keys to IVF pregnancy. Generally speaking, the implantation of fertilized eggs occurs 6-8 days after fertilization. After implantation, the embryo begins to secrete HCG, and its concentration will gradually increase with the progress of pregnancy.
About 6 days after embryo implantation, HCG can be detected in blood and 12-14 days in urine. Therefore, it can be confirmed that the fertilized eggs have successfully implanted and developed normally by detecting HCG.
HCG value detection time
In the IVF cycle, HCG detection is usually performed 12-14 days after embryo transfer. At this time, if the fertilized egg is successfully implanted and develops normally, the concentration of HCG will begin to rise. In some cases, doctors may request that the HCG value be tested again to ensure its normal growth.
It is worth noting that the detection time of HCG value is not constant. Different hospitals or doctors may have different testing schedules, depending on the actual situation.
Normal range of HCG value
The normal range of HCG values varies from individual to individual, but the normal range of HCG values measured from 12-14 days after embryo transfer is 25-100 IU/L. If the HCG value is less than 25IU/L, it may indicate that there may be problems in the development of the fertilized egg embedded in the uterus. Conversely, if the HCG value exceeds 100 IU/L, it may indicate that the number of fertilized eggs in pregnancy is a multiple pregnancy.
It should be noted that the HCG value can only be used as a reference indicator. In order to confirm the normal development of the embryo, doctors usually recommend other examinations, such as ultrasonic examination.
Possible causes of abnormal values
If the HCG value is abnormal, the following reasons may exist:
1. The fertilized egg is not successfully implanted or develops abnormally: if the HCG value is very low or fails to rise normally, it may indicate that the fertilized egg is not successfully implanted or develops abnormally, and the embryo may not continue to develop. This may be one of the reasons for the failure of IVF cycle.
2. Multiple fertilized eggs implantation: If the HCG value is abnormally high, it may indicate that multiple fertilized eggs have been successfully implanted, which increases the possibility of multiple pregnancies. Multiple pregnancy brings additional risks and challenges to both pregnant women and fetuses.
3. Pregnancy cyst or other diseases: abnormal HCG value may also be related to pregnancy cyst or other diseases. Pregnancy cyst is a kind of abnormal hormone secretion from ovary, which may lead to abnormal increase of HCG value.
Summary
The detection of HCG value of test tube baby can be used to judge whether the embryo develops normally. By reference to the implantation time of embryos, regular detection of HCG value and evaluation according to the standard of normal range can help determine the normal development of embryos. If the HCG value is abnormal, there may be development problems of embryo embedding in the uterus, increased possibility of multiple pregnancy, or the existence of other diseases. In the IVF cycle, close cooperation with doctors to monitor and evaluate the HCG value can improve the success rate of IVF pregnancy.
