Probability of postnatal malformations in test tube babies
In vitro fertilization (IVF) is a method of cultivating fertilized eggs in the laboratory and transplanting them into the mother's uterus to develop into a fetus. Many people have concerns and doubts about whether there is malformation in IVF after birth. In this article, we will discuss the probability of postnatal malformation of IVF from several aspects.
Influencing factors of congenital malformation
Congenital malformation refers to the abnormal body structure caused by genetic factors, environmental factors or other reasons in the process of fetal development. Whether it is a natural pregnancy or a test tube baby, the incidence of congenital malformations exists. According to statistics, the incidence of congenital malformations in the overall population is about 2% to 3%. There was no significant increase in the incidence of congenital malformations in IVF compared with natural pregnancy.
However, it should be noted that IVF may experience multiple tests and manipulations during pregnancy and embryonic development. These steps may increase the risk of some malformations. For example, infection, trauma or other complications may occur in the process of egg retrieval and embryo transfer, which may be related to embryonic malformation. Therefore, it is very important to select regular hospitals and experienced doctors for IVF operation.
Influence of genetic factors
Genetic factors play an important role in the occurrence of congenital malformations. Some chromosome abnormalities, gene mutations or genetic diseases may increase the risk of congenital malformations. The eggs and sperm used in IVF come from parents, and the genetic information they carry plays a decisive role in the development of the fetus.
In the process of embryo genetic diagnosis before IVF conception, doctors can screen embryos carrying high-risk genes such as genetic diseases through genetic screening and embryo chromosome testing, thus reducing the possibility of malformations. However, even if a comprehensive genetic screening is carried out, the occurrence of congenital malformations cannot be completely ruled out.
Influence of maternal age
Maternal age is one of the important factors that affect the rate of postnatal malformation of IVF. With the growth of women's age, the quality and quantity of eggs will gradually decline, thus increasing the risk of embryo chromosome abnormalities and congenital malformations. According to research, women over 30 years of age have an increased risk of congenital malformations during childbirth.
In order to reduce the influence of maternal age on congenital malformations, some young infertile couples may choose IVF technology. In this way, they can freeze the eggs when they are young and use them later when they need them, thus increasing the possibility of healthy development of embryos.
summary
In general, there is no significant increase in the rate of malformation of IVF after birth compared with natural pregnancy. The occurrence of congenital malformation is the result of multiple factors, including genetic factors, maternal age and so on. Selecting regular hospitals and experienced doctors for comprehensive genetic screening and embryo chromosome testing can reduce the risk of embryo malformation. In addition, early use of IVF technology can reduce the impact of maternal age on congenital malformations. For couples who dream of having children, IVF technology is a safe and effective choice.
