How to improve the success rate of IVF
In Vitro Fertilization (IVF) has become an effective method for infertile couples to achieve their fertility aspirations. However, the success rate of IVF is not 100%. In order to improve the success rate of IVF, the medical community continues to explore and use various related technologies and methods. This article will elaborate on the measures to improve the success rate of IVF from four aspects: pre pregnancy preparation, assisted reproductive technology, organ transplantation and genetic screening.
1、 Preparation before pregnancy
Preparation before pregnancy is crucial to the success rate of IVF. Before IVF, women should pay attention to adjusting their living habits, diet structure and weight to maintain a healthy life. Relevant research shows that women's overweight or underweight will affect the success rate of IVF. In addition, maintaining a good mood and reducing stress are also important factors.
In addition, men also need to make corresponding preparations before pregnancy. Men should avoid long-term exposure to high temperature environment, such as taking a hot bath for a long time, using a computer on the thigh, etc. These factors will have a negative impact on sperm quality. Reasonable diet, proper exercise and a balanced life schedule also have a positive impact on male fertility.
Scientific and reasonable preparation before pregnancy can improve the quality of female eggs and male sperm, thus increasing the success rate of IVF.
2、 Assisted reproductive technology
Assisted reproductive technology is one of the key links to improve the success rate of IVF. At present, the main assisted reproductive technologies include in vitro fertilization (ICSI), preimplantation genetic diagnosis (PGD), etc.
ICSI technology is one of the commonly used assisted reproductive technologies, which can overcome the problem of male infertility. This technology improves the fertilization rate and embryo quality by directly injecting a single sperm into the egg.
PGD is a method of genetic diagnosis before embryo implantation. PGD technology can screen genetic diseases carried by embryos, so as to avoid the inheritance of genetic diseases and improve the birth rate of healthy infants.
3、 Organ transplantation
Organ transplantation is another important technology to improve the success rate of IVF. At present, uterine transplantation has been successfully applied to the treatment of test tube babies. For those women who are infertile due to uterine dysplasia, hysterectomy or uterine dysfunction, uterine transplantation can restore their fertility. Sahlgrenska University Hospital in Sweden successfully performed the world's first uterine transplantation operation.
The success of organ transplantation has provided new fertility opportunities for patients with infertility without uterus, and also improved the success rate of IVF.
4、 Genetic screening
Genetic screening plays an important role in improving the success rate of IVF. Through genetic screening, patients with genetic diseases can be detected and healthy embryos can be selected for implantation, thus reducing the incidence of genetic diseases.
At present, some hospitals have developed gene sequencing technology, which can conduct comprehensive genetic screening of embryos. For example, Cold Spring Harbor Laboratory in the United States has carried out clinical genome diagnostic tests, using high-throughput gene sequencing technology to conduct accurate genetic screening of embryos.
Summary
The improvement of the success rate of IVF requires a variety of technologies and methods. Preparation before pregnancy can improve the patient's physical condition and improve the quality of eggs and sperm. Assisted reproductive technology, including ICSI and PGD, can improve fertilization rate and screen genetic diseases carried by embryos. Organ transplantation, especially uterine transplantation, provides new fertility opportunities for patients with infertility without uterus. Genetic screening can reduce the incidence of genetic diseases. The comprehensive application of these technologies and methods can significantly improve the success rate of IVF and help more infertile couples realize their reproductive dreams.
