Effect of Heparin on IVF
IVF refers to the baby obtained by in vitro fertilization through artificial assisted reproduction technology, and then embedding the fertilized egg into the mother's uterus to continue to develop. In order to ensure the success rate of IVF and promote embryo implantation, some hospitals use heparin treatment, which can play a positive role in the success rate of IVF. The following is the role of heparin in IVF:
1. Improve embryo implantation
Implantation of IVF in uterus is a key step for successful pregnancy. Heparin can improve embryo implantation through a series of biological effects. First, heparin can inhibit platelet aggregation, reduce platelet aggregation and blood clot formation in endometrium, and provide a better implantation environment. Secondly, heparin can reduce blood viscosity, promote maternal blood circulation, thereby increasing endometrial blood perfusion, which is conducive to embryonic development and implantation. Finally, heparin has anti-inflammatory effect, reduces the inflammatory reaction of endometrium, and is helpful for embryo implantation.
2. Prevention of embryonic immune response
In IVF patients, it is more common that embryo immune reaction leads to difficulty in embryo implantation. Heparin can prevent embryonic immune reaction by regulating the function of immune system. Heparin can inhibit the autoimmune reaction, reduce the production of autoantibodies, and reduce embryonic immune damage. In addition, heparin can also regulate the function of immune cells, increase the number of immune regulatory cells (Treg cells), inhibit the activation of immune cells (Th17 cells), maintain immune balance, and reduce the risk of immune injury.
3. Reduce the risk of abortion
Abortion is one of the common complications in IVF patients. The use of heparin can help reduce the risk of miscarriage. Heparin can reduce the risk of abortion by inhibiting platelet aggregation, reducing blood viscosity, improving endometrial blood flow and regulating immune system function. In addition, heparin can also inhibit thrombosis and prevent the occurrence of thromboembolism in pregnant women. Taken together, these effects can improve the pregnancy rate and success rate of IVF.
4. Safety and effect
Heparin therapy for IVF is widely used in clinical practice, and its safety and effect have been verified. Heparin, as a commonly used anticoagulant, its dosage and use method have been extensively studied and explored. Clinical studies have shown that heparin treatment can significantly improve the embryo implantation rate and fertility rate in test tube infants, and no obvious safety problems have been found in the study. At present, heparin has been used as a standard adjuvant in IVF treatment in many real hospitals.
In conclusion, IVF heparin can improve embryo implantation, prevent embryo immune response, and reduce the risk of abortion. Heparin therapy in IVF has been proved to be safe and effective. The use of this adjuvant drug can improve the success rate of IVF and bring more hope and joy to couples who wish to become parents.
