IVF, also known as assisted reproductive technology, refers to helping couples who cannot conceive in a natural way to achieve their reproductive aspirations through in vitro fertilization (IVF), embryo transfer and other methods.The specific process of IVF will be introduced in detail below, including treatment preparation, egg collection and fertilization, embryo culture and selection, and embryo transfer.
Preparation for treatment
Preparation for IVF treatment is a very important part of the whole process.First of all, both husband and wife need to have a comprehensive physical examination, including the evaluation of reproductive organ function, endocrine system and other aspects.Secondly, women need to have endometrial thickness tests and ovarian function tests to determine whether IVF treatment can be carried out.The man shall provide semen samples for sperm quality assessment.In addition, both husband and wife need to receive psychological counseling to understand the physical and psychological pressure in the treatment process, as well as the possible treatment risk and success rate.In the preparation stage, the couple also need to choose a regular hospital with relevant professional experience for treatment.For example, the Assisted Reproduction Center of Peking Union Medical College Hospital is one of the most authoritative IVF hospitals in China.When selecting hospitals, we should consider the hospital's reputation, equipment and technical level, as well as whether there are bad records and other information.
Egg collection and fertilization
After treatment preparation, women enter the stage of ovarian stimulation.Through the injection of ovulation promoting drugs, ovarian development is promoted and multiple mature follicles are produced.During this period, doctors will regularly monitor the follicular development according to the size and number of follicles to determine the best time for egg collection.Egg collection is one of the core steps in IVF.In the operating room, doctors use ultrasound guidance to puncture a thin needle into the ovary to extract fluid from the follicle.This process is usually carried out under local anesthesia. For most women, it only takes 15-30 minutes to complete.The eggs collected will be sent to the laboratory for fertilization.There are two common ways of fertilization: one is to culture fresh sperm and eggs together in nutrient solution, waiting for natural fertilization;The other is artificial fertilization by injecting an active sperm into the egg.
Embryo culture and selection
After fertilization, the eggs will continue to be cultured.In the laboratory, the embryo incubator will provide an environment similar to endometrium to promote embryo development.Embryo culture usually lasts for 3-5 days, and doctors will decide the best time for embryo transfer according to the quality and quantity of embryos.During the culture process, the doctor will evaluate the embryo.Routine evaluation indexes include the number, evenness and division quality of embryonic cells.Modern technology can also screen more healthy and developmental potential embryos through gene screening and other means to improve the success rate.
embryo transfer
Embryo transfer is the last and most critical step in IVF treatment.The doctor will insert the embryo with the most development potential into the female uterus through a thin tube and locate it in the most suitable position.This process is usually performed under local anesthesia and does not require hospitalization.After embryo transfer, doctors usually advise women to continue taking progesterone and other drugs to promote the stability of endometrium and the continued development of pregnancy.After about two weeks, women can conduct a blood pregnancy test to determine whether the pregnancy is successful.
Summary
The process of IVF can be divided into four main aspects: treatment preparation, egg collection and fertilization, embryo culture and selection, and embryo transfer.Treatment preparation includes physical examination and psychological counseling. Egg collection is the core step. Fertilization methods include natural fertilization and artificial fertilization. Embryo culture and selection are the key links to determine the quality and quantity of embryos, and embryo transfer is the final key step.To sum up, through reasonable treatment preparation and meticulous operation, IVF technology can help many couples who cannot conceive naturally achieve their fertility aspirations.
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