Title: Restrictions of IVF on Sperm 1. Semen quality
Semen quality is one of the important factors that determine the success rate of IVF. Semen quality includes sperm quantity, sperm motility and morphological abnormality rate. Insufficient sperm may lead to difficulty in fertilization, while low sperm activity will affect the ability of sperm to enter the egg. In addition, sperm with a high rate of morphological abnormalities may affect the development and implantation of embryos. Therefore, semen quality is a limiting factor that must be paid attention to during IVF.
In order to improve semen quality, some hospitals will take a series of measures. For example, appropriate nutrition supplements and lifestyle adjustments should be given to reduce or avoid exposure to harmful substances that affect sperm quality, such as tobacco, alcohol and drugs. In addition, sperm quality improvement techniques, such as sperm selection, sperm culture and freezing, can also improve semen quality.
2. Sperm survival time
The survival time of sperm is another limiting factor in the process of fertilization. The survival time of sperm in the female reproductive tract is limited, usually ranging from several hours to several days. If the sperm loses its vitality before entering the egg, it will not be able to fertilize successfully. Therefore, it is very important to ensure the accuracy of fertilization time in IVF treatment.
In order to solve the limitation of sperm survival time, hospitals usually use assisted fertilization technology, such as in vitro maturation and fertilization (IVM/IVF) of eggs. These techniques can realize the fertilization process under the condition of short sperm survival time, and improve the success rate of IVF.
3. Sperm motility
The motility of sperm is one of the important factors that determine whether sperm can successfully reach the egg. Sperm needs to have good swimming ability to quickly pass through various resistances of female reproductive tract and finally reach the egg for fertilization. If sperm motility is insufficient, fertilization will be difficult.
In order to improve sperm motility, hospitals usually test and evaluate sperm motility to select sperm with better motility for IVF treatment. In addition, some auxiliary technologies, such as artificial insemination (IUI) and pregnancy aid, can also improve sperm motility.
4. Sperm genetic abnormality
Sperm genetic abnormality is an important limiting factor, which may lead to genetic diseases in newborns. Sperm genetic abnormalities mainly include chromosome abnormalities and gene mutations. If sperm carries chromosome abnormalities or gene mutations, it is likely to lead to abnormal embryonic development, fetal malformations or infant genetic diseases.
In order to avoid the influence of sperm genetic abnormalities on IVF, hospitals usually carry out sperm genetic testing. Sperm genetic testing can screen sperm carrying chromosome abnormalities or gene mutations, and take corresponding intervention measures, such as gene editing technology, selective fertilization, etc., to reduce the risk of genetic diseases.
In conclusion, IVF has many restrictions on sperm. Semen quality, sperm survival time, sperm motility and sperm genetic abnormalities may affect the success rate of IVF. However, with the continuous progress of technology and the development of medicine, hospitals are constantly applying new technologies and methods to overcome these limitations and improve the success rate of IVF.
