The relationship between the risk of elder childbearing and malformation
With the development of social economy and the progress of medical technology, more and more women choose to postpone childbearing. However, the elderly childbearing also brings a series of risks, including the increase of infant malformations. This article will elaborate on the relationship between the risk of elder childbearing and malformation from reproductive health, gene mutation, pregnancy complications and postpartum care.
1、 Reproductive health
With the growth of women's age, the ovarian function will gradually decline. The number and quality of women's eggs will also decrease, leading to a decline in fertility. In addition, the decline of ovarian function will also increase the risk of early abortion and chromosomal abnormalities. A study shows that the probability of chromosomal abnormalities is higher in children born to women over 35 years old.
In addition, the responsiveness of the endometrium of elderly women to hormones will decline, leading to difficulty in implantation. This is also an important reason for the infertility of elderly women. If pregnancy is still achieved through artificial insemination, the natural aging of endometrium may increase the risk of pregnancy complications.
Moreover, the physical functions of elderly women gradually decline, including cardiovascular, metabolic and immune systems. These physiological changes will also increase the risk of complications during pregnancy.
2、 Gene mutation
The risk of chromosomal abnormalities in female eggs increases with age. Chromosome abnormalities may lead to the termination of embryo development or congenital malformations. Common chromosomal abnormalities include Down syndrome, Edwards syndrome and mental retardation. Research shows that the probability of chromosomal abnormalities is significantly increased in children born to women over 35 years old.
In addition, long-term exposure to environmental pollution, radiation, drugs or chemicals can also lead to gene mutations. Older women are exposed to various adverse environmental factors for a longer time, and the risk of gene mutation is correspondingly increased.
3、 Pregnancy complications
Older pregnant women have a higher risk of pregnancy complications such as gestational diabetes, pregnancy hypertension and amniotic fluid embolism, which will have a serious impact on the health of the fetus and mother. Gestational diabetes will increase the risk of fetal macrosomia, pregnancy hypertension will lead to fetal growth retardation, and amniotic fluid embolism may lead to fetal distress or even death.
In addition, abnormal fetal implantation, placental abruption and other conditions commonly seen in prenatal examination of elderly pregnant women will also increase the risk of fetal malformation.
4、 Postpartum care
With the growth of age, women's physical strength, immunity and self-healing ability will gradually decline. The recovery speed of the elderly parturient is slow in the recovery process after childbirth, which is prone to psychological problems such as postpartum depression. These problems may affect the maternal care and nursing of newborns and increase the risk of abnormal development of infants.
In a word, the elderly childbearing does increase the risk of pregnancy and the possibility of infant malformation. When considering giving birth at an advanced age, women should fully understand these risks and actively take relevant measures to reduce the risks, such as conducting prenatal examination in advance, maintaining good living habits, and strengthening physique. The professional advice and careful care of doctors are also the key to ensure the health of elderly mothers and fetuses.
