Contraindications of second-generation IVF
As an assisted reproductive technology, the second-generation IVF technology has solved the fertility problem for some infertile couples, but it is not applicable to all people. According to the patient's physical condition and the doctor's professional opinion, there are some contraindications, so it is not recommended to carry out second-generation IVF. The following will elaborate on the contraindications of second-generation IVF in terms of genetic diseases, reproductive tract problems, major diseases and psychological factors.
Genetic disease
Genetic disease is an important contraindication of the second generation IVF. If one or both parties suffer from specific genetic diseases, such as hereditary muscular dystrophy, cystic fibrosis, etc., the second generation of IVF will bring about the transmission of high-risk genetic diseases. When the family history of genetic disease is obvious, the doctor will advise couples to avoid second generation IVF.
In addition, some autosomal dominant and dominant genetic diseases are also contraindications of second-generation IVF. For example, when it is applicable to genetic diagnosis of pre implanted embryos with gene mutation of autosomal genetic diseases, if the embryo is found to carry abnormal genes, the doctor will recommend abandoning the transfer.
Reproductive tract problems
Reproductive tract problems are also a common contraindication of second-generation IVF. Women with severe uterine malformations (such as bicorned uterus and monocorned uterus) and obvious fallopian tube problems (such as fallopian tube obstruction and displacement) will affect the successful insertion of fertilized eggs into the uterus. In this case, the second-generation IVF may not be successfully implemented.
For men, if the semen quality is very poor and they cannot provide enough sperm for assisted reproductive technology, they will also be identified as contraindications. This may be caused by low sperm count, abnormal sperm morphology or poor motility.
Major diseases
Suffering from serious diseases is also one of the contraindications of second-generation IVF. For example, some chronic diseases may lead to pregnancy complications or not conducive to embryonic development, such as systemic lupus erythematosus, severe hypertension, severe heart disease, etc. In this case, the doctor may suggest that the patient is not suitable for second-generation IVF to avoid increasing the risk of pregnancy.
In addition, the treatment of cancer and other major diseases may require the use of some drugs or radiotherapy that are potentially dangerous to embryonic development, which is also a contraindication for second-generation IVF.
psychological factor
In addition to physiological contraindications, psychological factors are also one of the factors to be considered for the second generation of IVF. If couples are not psychologically ready to accept the process of assisted reproductive technology, as well as potential failure and psychological pressure, doctors may recommend not carrying out second-generation IVF for the time being.
In addition, factors such as marital relationship and family environment between infertile couples will also affect the decision-making of the second generation IVF. If there are serious marital problems or family instability factors between couples, doctors may suggest that these problems be solved before considering assisted reproductive technology.
summary
The second-generation IVF technology has brought hope to infertile couples, but it is not applicable to everyone. Genetic diseases, reproductive tract problems, major diseases and psychological factors are all contraindications for second-generation IVF.
Therefore, when choosing whether to carry out second-generation IVF, patients should fully understand their own conditions and the professional advice of doctors to ensure the best treatment effect.
