Causes of multiple pregnancy in test tube infants
In vitro multiple pregnancy means that there are more than two fetuses in the pregnancy generated by assisted reproductive technology (such as in vitro fertilization embryo transfer). Multiple pregnancy is a special kind of pregnancy, and its causes involve many factors.
Reason 1: In vitro fertilization procedure
The IVF procedure of IVF involves several steps, including egg collection, sperm egg combination and embryo culture. In the process of combining eggs and sperm, the surplus embryos may be retained and implanted into the uterus with the advice of reproductive experts. This process increases the risk of multiple pregnancies.
In addition, in order to increase the success rate, doctors will implant multiple embryos in women. Because not all implanted embryos can be successfully implanted and developed, in order to improve the success rate, doctors will implant multiple embryos in the uterine cavity, so that at least one embryo can be successfully implanted. However, it also increases the risk of multiple pregnancies.
In addition, the occurrence of IVF multiple pregnancy is also related to implantation technology. Different implantation techniques have different success rates and multiple pregnancy risks. For example, the traditional embryo implantation technology will increase the possibility of multiple pregnancy, while the emerging single embryo implantation technology can reduce the risk of multiple pregnancy.
Reason 2: Age and ovarian reactivity
Age and ovarian responsiveness also have some influence on the occurrence of multiple pregnancy. The number and quality of female eggs gradually decline with age. In order to increase the chance of successful pregnancy, doctors may stimulate ovarian hyperstimulation during IVF. This means that women will produce more eggs, thus increasing the possibility of multiple pregnancies.
In addition, ovarian responsiveness to drugs may also affect the risk of multiple pregnancy. Some women have a high response to hormone drugs, resulting in multiple eggs produced by the ovary. This will also increase the risk of multiple pregnancies.
Cause 3: genetic factors
The occurrence of IVF multiple pregnancy is also related to genetic factors. Some women carry specific genetic variations that increase the risk of multiple pregnancies. For example, genetic variations carried by some women may lead to abnormal ovulation process, resulting in simultaneous release of multiple eggs.
In addition, some genetic factors will also affect the quality and quantity of embryonic development, increasing the possibility of multiple pregnancy. For example, some gene variations may lead to abnormal embryo division, which may lead to twins or multiple births.
Reason 4: Personal choice and needs
There are also multiple pregnancies due to personal choices and needs. Some families hope to have multiple children, so they deliberately choose to implant multiple embryos in the process of IVF. In addition, some families worry about the possibility of pregnancy failure and hope to increase the chance of success by implanting multiple embryos.
In conclusion, there are many reasons for IVF multiple pregnancy, including IVF procedure, age and ovarian reactivity, genetic factors, and individual choice and needs. Understanding these reasons can help us better understand the mechanism of multiple pregnancy, and provide reference for related medical technology and safety measures.
