What are the blood type requirements of IVF for parents?
IVF refers to the process of completing fertilization and embryo culture in vitro through assisted reproductive technology, and then implanting the embryo into the mother to make it pregnant and deliver successfully. In the process of IVF, the combination of parents' blood types is an important consideration. Parents with different blood types also have slightly different precautions and risks.
ABO blood group system
The ABO blood group system is a common way to classify blood groups. According to different antigens and antibodies in body fluids, blood groups are divided into A, B, AB and O. When selecting a suitable combination of IVF blood types, the following points should be noted:
1. ABO blood type mismatch may lead to hemolysis: in some cases, parents' blood type mismatch may lead to hemolytic reaction in infants. Especially when the mother is type O and the father is type A, B or AB, the risk of hemolysis of the baby is higher. Therefore, in order to avoid the risk of hemolysis, doctors will conduct relevant blood type identification and monitoring during IVF.
2. Consider the genetic law of AB parents: if at least one parent is AB, the baby's blood type may be A, B, AB or O. Since AB can accept transfusion of other blood types, AB parents are relatively relaxed in blood type selection.
3. Blood type selection of type O parents: Since the antigen of type O blood is well compatible with antibodies of other blood types, type O parents are relatively flexible in the process of IVF. They can be combined with spouses of any blood type without worrying about hemolysis.
Rh blood group system
Rh blood group system is classified according to different Rh blood group antigens in human blood. Rh blood group mainly includes Rh positive and Rh negative. In the selection of test tube baby blood type, the following points should be noted:
1. One of the parents is Rh negative: if one of the parents is Rh negative and the other is Rh positive, the baby may inherit Rh positive, and there is a risk of Rh blood type mismatch. In this case, if the mother is Rh negative, it is possible to produce maternal antibodies that are incompatible with Rh blood group. Doctors will take immune prevention measures during IVF to avoid risks caused by incompatibility of Rh blood group during pregnancy.
2. Both parents are Rh negative: if both parents are Rh negative, then the baby is Rh negative, and there is no risk of Rh blood group mismatch. In this case, parents are relatively more flexible in choosing the blood type of IVF.
Other blood group related factors
In addition to ABO and Rh blood group systems, there are other factors related to blood group that need to be considered:
1. Rhesus C, E antigen and Du's antigen: the existence of these antigens is related to the mother's immune response. In the process of IVF, doctors will test these antigens of parents to determine the blood group combination of the baby.
2. Platelet count and coagulation function: It is related to the coagulation function of mother and infant and the risk of postpartum hemorrhage. Doctors will evaluate these factors during IVF to ensure the health and safety of mothers and infants.
summary
The ABO and Rh blood group systems are the most important factors to consider when selecting a combination of test tube baby blood groups. The combination of parents with different blood types may affect the hemolysis risk and Rh blood group mismatch of infants. In addition, other blood group related factors such as Rhesus antigen and coagulation function also need to be considered. Therefore, in the process of IVF, doctors will carry out relevant tests and evaluations to ensure the health and safety of infants.
