Required content of IVF test
IVF examination refers to the process of transferring fertilized eggs into the mother's uterus through artificial assisted reproduction technology to make them develop into embryos, and finally realize pregnancy and delivery. In order to ensure the healthy and successful development of IVF, doctors need to carry out a series of examinations and evaluations. This article will elaborate on the necessary contents of IVF examination from four aspects: genetic examination, physical examination, embryo evaluation and pregnancy management.
Genetic examination
Genetic testing is an important part of IVF screening. It can help doctors assess whether embryos carry genetic diseases or chromosomal abnormalities. First, doctors will carry out genetic tests on both spouses to determine the risk of genetic diseases. Gene testing can include blood testing or saliva sampling. Then, in the early stage after artificial insemination, doctors will take samples from embryonic cells for chromosome analysis and gene mutation screening. This test can help determine whether the embryo has chromosomal abnormalities, such as Down syndrome. Based on the results of genetic examination, doctors can select healthy embryos for transplantation to improve the success rate of IVF.
In addition, some couples with monogenic genetic diseases may choose to conduct gene editing of the patient or the fertilized egg to prevent the transmission of genetic diseases. However, this gene editing technology is still in the research stage, and its clinical application is relatively limited.
physical examination
Physical examination is another important part of IVF examination, which can help doctors assess the overall health of mother and embryo. This inspection generally includes the following contents:
1. Detailed medical history and comprehensive physical examination of the mother, including height, weight, blood pressure, cardiopulmonary function, etc.
2. Gynecological examination, understand the condition of uterus and ovary, and exclude any abnormality that may affect the pregnancy of test tube baby.
3. The semen analysis of the man to evaluate factors such as sperm quantity, quality and vitality.
Through comprehensive analysis of the physical examination results, doctors can determine whether the mother is suitable for the IVF process and determine the best mode of assisted reproductive technology.
Embryo evaluation
In the process of IVF, embryo evaluation is the key to ensure healthy embryo selection and successful transfer.
1. Embryo culture: After in vitro fertilization, embryos will be cultured in culture dishes. Doctors will regularly observe the development of the embryo and evaluate its cell division speed and morphological characteristics.
2. Chromosome screening: doctors can conduct non-invasive chromosome screening on embryos through embryo biopsy or embryo cells in embryo culture medium. This can help determine whether there are chromosomal abnormalities in embryos, so as to select healthy embryos for transfer, and reduce the risk of embryo implantation failure and birth defects.
3. Genetic screening: In addition to the genetic screening mentioned above, doctors may also use other strategies, such as single cell PCR or NGS, to conduct a more comprehensive genetic screening of embryos to assess the risk of genetic diseases.
Pregnancy management
Once healthy embryos are successfully transferred, pregnancy management will become a key link in the IVF process.
1. Early pregnancy monitoring: Doctors will monitor the early pregnancy after embryo transfer by detecting progesterone and human chorionic gonadotropin (hCG) levels in blood.
2. Health care during pregnancy: The doctor will provide guidance on health care during pregnancy, including precautions for diet, exercise and drugs.
3. Blood examination and ultrasound examination during pregnancy: The doctor will conduct blood examination and ultrasound examination during pregnancy regularly to ensure the normal progress of pregnancy and eliminate any possible complications.
To sum up, the necessary contents of IVF examination include genetic examination, physical examination, embryo evaluation and pregnancy management. Through these examinations and assessments, doctors can provide personalized diagnosis and treatment programs to maximize the health and successful development of IVF.
