Screening and testing items of test tube babies
IVF refers to the implantation of fertilized eggs into the mother through assisted reproductive technology in the process of IVF, so that couples who cannot conceive naturally can have their own children. In order to ensure the health of IVF, a series of screening and testing are needed. The following four aspects will be introduced in detail: pre pregnancy screening, embryo screening, pregnancy screening and post birth screening.
1. Pre pregnancy screening
The purpose of pre pregnancy screening is to find out whether there are chromosome abnormalities and genetic diseases on both sides of the couple, so as to prevent the transmission of genetic diseases to the next generation. In pre pregnancy screening, chromosome karyotype analysis, single gene disease screening and genetic counseling are usually carried out.
Chromosome karyotype analysis is to detect the number and structure of chromosomes by collecting blood samples or amniotic fluid cells from couples, which can exclude chromosome abnormalities, such as Down syndrome. Single gene disease screening is to determine whether there is a gene mutation of a certain genetic disease through gene testing of couples. Genetic counseling is to assess the genetic risk of a couple according to their genetic and family history, and provide corresponding advice and suggestions.
2. Embryo screening
Embryo screening is a key part of IVF. By testing the fertilized eggs, embryos with chromosome abnormalities, genetic diseases or other fatal diseases are screened to ensure that healthy embryos are selected for implantation.
Embryo screening usually includes embryo quality assessment, chromosome screening and genetic disease screening. The embryo quality assessment mainly evaluates the developmental potential of the fertilized egg by observing its cell division, embryo morphology and development degree. Chromosome screening adopts PGS (Embryo Chromosome Screening) technology to detect the number and structure of chromosomes in embryos, so as to exclude the implantation of embryos with abnormal chromosomes. Genetic disease screening is to determine whether an embryo carries a genetic disease through gene mutation detection.
3. Pregnancy screening
The purpose of pregnancy screening is to detect the health status of the pregnant women and the development of the fetus, find out the abnormal situation in time and take corresponding measures. Pregnancy screening usually includes prenatal examination, four-dimensional color ultrasound and prenatal screening.
Prenatal examination is a series of examinations for pregnant women themselves, including routine tests, urine tests, blood pressure monitoring, etc., to ensure the health of pregnant women. The four-dimensional color ultrasound can observe the development of the fetus, including organ morphology, movement, heart, brain, etc., and can detect the abnormal development of the fetus as soon as possible. Prenatal screening uses a combination of blood testing and ultrasound to assess whether there are chromosomal abnormalities and common genetic diseases in the fetus.
4. Postnatal screening
Postnatal screening is to find the possible diseases of newborns at birth as soon as possible, as well as some diseases that need early intervention. Postnatal screening usually includes hearing screening, neonatal disease screening and heart screening.
Hearing screening is to detect the hearing response of newborns and find out hearing impairment early so as to carry out corresponding intervention as soon as possible. Neonatal disease screening is to detect metabolic diseases, thyroid dysfunction and other aspects of neonatal blood samples, so as to find related diseases as early as possible. Cardiac screening is to carry out echocardiographic examination on the heart of newborns to exclude congenital heart disease.
Summary
Test tube babies need a series of screening and testing, including pre pregnancy screening, embryo screening, pregnancy screening and postnatal screening. Through these screening and testing projects, we can ensure the health of test tube babies and reduce the risk of birth defects and genetic diseases. These screening and testing programs have been widely used in many formal reproductive hospitals, providing reliable technical support for couples to realize their reproductive dreams.
